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Living biological systems display a fascinating ability to self-organise their metabolism. This ability ultimately determines metabolic robustness that is fundamental to control cellular behaviour. However, fluctuations in metabolism can affect cellular homeostasis through transient oscillations. Fo...
ORGANISM(S): Clostridium autoethanogenum 
2020-05-18 | PXD016381 | Pride
Impact of fluctuating environments on the fitness and robustness of evolving laboratory and industrial Saccharomyces cerevisiae strains.
Drosophila Modulo is Essential for Transposon Silencing and Developmental Robustness.
This study describes a transcriptome-phenotype matching approach in which the starter L. lactis MG1363 was fermented under a variety of conditions that differed in the levels of oxygen and/or salt, as well as the fermentation pH and temperature. Samples derived from these fermentations in the expone...
ORGANISM(S): Lactococcus lactis subsp. cremoris MG1363 
Biological systems display extraordinary robustness. Robustness of transcriptional enhancers results mainly from clusters of binding sites for the same transcription factor, and it is not clear how robust enhancers can evolve loss of expression through point mutations. Here, we report the high-resol...
ORGANISM(S): Drosophila melanogaster 
2018-04-28 | GSE80790 | GEO
Adaptation to diverse transcription factor knockouts reveals robustness of transcription regulatory network
Recently, we demonstrated that fermentation conditions strongly impact on subsequent survival of Lactococcus lactis strain MG1363 during heat and oxidative stress, two important parameters during spray drying. Moreover, employment of a transcriptome-phenotype matching approach revealed groups of gen...
ORGANISM(S): Lactococcus lactis Lactococcus cremoris subsp. cremoris SK11 
2015-12-24 | GSE72044 | GEO
Recently, we demonstrated that fermentation conditions strongly impact on subsequent survival of Lactococcus lactis strain MG1363 during heat and oxidative stress, two important parameters during spray drying. Moreover, employment of a transcriptome-phenotype matching approach revealed groups of gen...
ORGANISM(S): Lactococcus lactis Lactococcus lactis subsp. lactis KF147 
2015-12-24 | GSE72043 | GEO
Recently, we demonstrated that fermentation conditions strongly impact on subsequent survival of Lactococcus lactis strain MG1363 during heat and oxidative stress, two important parameters during spray drying. Moreover, employment of a transcriptome-phenotype matching approach revealed groups of gen...
ORGANISM(S): Lactococcus lactis Lactococcus lactis subsp. lactis Il1403 
2015-12-24 | GSE72042 | GEO
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