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TranscriptomicsEscherichia coli global gene expression in urine from women with urinary tract infection
Examination of E. coli transcripts present in bacteria in urine samples from 8 patients attending a urology clinic with symptoms of cystitis, as compared to transcripts present in the same E. coli strains during mid-exponential growth in filter-sterilized human urine in vitro. A 48 array study using...
ORGANISM(S): Escherichia coli 
2010-11-12 | E-GEOD-24478 | biostudies-arrayexpress
GenomicsMsn2-mediated nucleosome remodeling dynamics
The aim of this experiment was to determine, using MNAse-Seq, how nucleosomes get remodeled during an Msn2 activation timecourse genome-wide. Diploid strain EY2807/ASH79 with genotype TPK1M164G TPK2M147G TPK3M165G msn4::TRP1/LEU2 MSN2-mCherry NHP6a-iRFP::kanMX was used. This strain is PKAas, so upon...
ORGANISM(S): Saccharomyces cerevisiae 
2013-10-12 | E-MTAB-1950 | biostudies-arrayexpress
UnknownOn a Cold Night: Transcriptomics of Grapevine Flower Unveils Signal Transduction and Impacted Metabolism.
Not available
S-EPMC6429367 | biostudies-literature
TranscriptomicsTranscription profiling of human MCF7 breast cancer cell line treated with dioxin and DMSO control
MCF7 cells were treated with DMSO or 100 nM Dioxin for 16 hr. Gene expression changes were quantified by microarray analyses. Experiment Overall Design: HU133A and B arrays were used to quantify differences in RNA after treatment with 100 nM dioxin for 16 h. The experiment was repeated 3 times.
ORGANISM(S): Homo sapiens 
2007-10-31 | E-GEOD-7765 | biostudies-arrayexpress
GenomicsHog1 controls global reallocation of RNA Pol II upon osmotic shock
When challenged with osmotic shock, S. cerevisiae induces hundreds of genes, despite a global reduction in transcriptional capacity. The mechanisms that regulate this rapid reallocation of transcriptional resources are not known. Here we show that redistribution of RNA Pol II upon stress requires ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-15 | E-GEOD-38208 | biostudies-arrayexpress
TranscriptomicsRestoring miR-200c to aggressive endometrial cancer cell line
Using a mimic miR-200c was restored to an aggressive, Type 2 endometrial cancer cell line, Hec50 We sought to identify genes regulated by miR-200c in an aggressive cancer.
ORGANISM(S): Homo sapiens 
2010-11-17 | E-GEOD-25332 | biostudies-arrayexpress
TranscriptomicsA high resolution map of a cyanobacterial transcriptome
Previous molecular and mechanistic studies have identified several principles of prokaryotic transcription, but less is known about the global transcriptional architecture of bacterial genomes. Here we perform a comprehensive study of a cyanobacterial transcriptome, that of Synechococcus elongatus P...
ORGANISM(S): Synechococcus elongatus PCC 7942 
2011-05-16 | E-GEOD-29264 | biostudies-arrayexpress
TranscriptomicsUPC2 Is universally essential for Azole antifungal resistance in Candida albicans
In Candida albicans, the transcription factor Upc2 is central to the regulation of ergosterol biosynthesis. UPC2-activating mutations contribute to azole resistance, whereas disruption increases azole susceptibility. In the present study, we investigated the relationship of UPC2 to fluconazole susce...
ORGANISM(S): Candida albicans 
2014-05-24 | E-GEOD-57929 | biostudies-arrayexpress
TranscriptomicsThe transcriptional regulator Cas5 influences the susceptibility of Candida albicans to Fluconazole.
Azole antifungal agents such as fluconazole exhibit fungistatic activity against Candida albicans. Strategies to enhance azole antifungal activity would be therapeutically appealing. In an effort to identify transcriptional pathways that influence fluconazole susceptibility, we sought to identify ...
ORGANISM(S): Candida albicans 
2014-05-24 | E-GEOD-57930 | biostudies-arrayexpress
GenomicsChIP-Seq analysis of RpaA binding dynamics
The response regulator RpaA is required for control of genome-wide gene expression by the cyanobacterial circadian clock. RpaA is predicted to be a DNA binding protein based on sequence homology, but prior studies have been unable to detect binding in vitro or in vivo to a small panel of promoters....
ORGANISM(S): Synechococcus elongatus PCC 7942 
2013-12-04 | E-GEOD-51093 | biostudies-arrayexpress
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