Sort   by:  
 Page size 
UnknownSeven direct methods for measuring HDL and LDL cholesterol compared with ultracentrifugation reference measurement procedures.
Not available
S-EPMC4687457 | biostudies-literature
UnknownNon-HDL cholesterol shows improved accuracy for cardiovascular risk score classification compared to direct or calculated LDL cholesterol in a dyslipidemic population.
Not available
S-EPMC4684263 | biostudies-literature
TranscriptomicsTranscription profiling of mouse model of intestinal polyposis PTEN-deficient mutant reveals intestinal stem cells initiate intestinal polyposis
Intestinal polyposis, a precancerous neoplasia, results primarily from an abnormal increase in the number of crypts. Crypts contain intestinal stem cells (ISCs). Thus intestinal polyposis provides an ideal condition for studying stem cell involvement in polyp/tumor formation. Using a conditional kno...
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-6078 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat synaptosomes of the hippocampus vs. total hippocampus reveals activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites
Mammalian target of rapamycin (mTOR) is implicated in synaptic plasticity and local translation in dendrites. Here we found that the mTOR inhibitor, rapamycin, increased the Kv1.1 voltage-gated potassium channel protein in hippocampal neurons and promoted Kv1.1 surface expression on dendrites withou...
ORGANISM(S): Rattus norvegicus 
2008-06-13 | E-GEOD-5516 | biostudies-arrayexpress
TranscriptomicsMicroRNA-520c-3p targets eIF4GII and acts as a tumor suppressor in diffuse large B cell lymphoma
Deregulation of the translational machinery is emerging as a critical contributor to lymphomagenesis. Various miRNA alterations have been identified in lymphoma, but their role in disrupting the cap-dependent translation regulation complex remains poorly understood. Here, we demonstrate the translat...
ORGANISM(S): Homo sapiens 
2014-03-19 | E-GEOD-40489 | biostudies-arrayexpress
TranscriptomicsCytoplasmic MTDH associates with mRNAs
To examine whether MTDH is a novel RNA binding protein and regulates either metabolism or translation of various mRNAs, we performed a RNA-binding protein immunoprecipitation (RIP) with MTDH and IgG antibodies, and the resulting immunoprecipitated RNA was subjected to a microarray to identify transc...
ORGANISM(S): Homo sapiens 
2011-07-12 | E-GEOD-30588 | biostudies-arrayexpress
TranscriptomicsExpression data from MTDH knockdown in the Hec50co endometrial cancer cell line
Understanding the molecular underpinnings of chemoresistance is vital to design therapies to restore chemosensitivity. In particular, metadherin (MTDH) has been demonstrated to have a critical role in chemoresistance. Over-expression of MTDH has recently been implicated in poor clinical outcome in b...
ORGANISM(S): Homo sapiens 
2010-12-17 | E-GEOD-26134 | biostudies-arrayexpress
UnknownBrief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians.
Not available
S-EPMC3670944 | biostudies-literature
GenomicsGlobal Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (ChIP-Seq)
T follicular helper (Tfh) cells are a subset of CD4+ T helper (Th) cells that migrate into germinal centers and promote B cell maturation into memory B and plasma cells. Tfh cells are necessary for promotion of protective humoral immunity following pathogen challenge, but when aberrantly regulated, ...
ORGANISM(S): Homo sapiens 
2014-10-27 | E-GEOD-58595 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in Nalm6 ALL leukemia cells
Identify the expression intensity for all genes in Nalm6 cells and all the genes are divided into 4 equal groups with group 1 containing the 25% of genes that were expressed at the highest levels, and group 4 containing the 25% of genes that were expressed at the lowest levels. Total RNA are isolate...
ORGANISM(S): Homo sapiens 
2015-11-03 | E-GEOD-44214 | biostudies-arrayexpress
Sort   by:  
 Page size