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UnknownPioneering first-in-class HDAC-ROCK inhibitors as potential multitarget anticancer agents.
Not available
S-EPMC11834526 | biostudies-literature
TranscriptomicsS080_BrCaRes_Schneeweiss et al.
In patients with primary breast cancer, neoadjuvant chemotherapy with doxorubicin plus pemetrexed followed by docetaxel (AP-D) is associated with a pathologic complete response (pCR) rate of 16.5%, and doxorubicin plus cyclophosphamide followed by docetaxel (AC-D) is associated with a pCR rate of 20...
ORGANISM(S): Homo sapiens 
2014-02-01 | E-TABM-1186 | biostudies-arrayexpress
UnknownActivation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease.
Not available
S-EPMC3820652 | biostudies-literature
UnknownA novel mechanism of inhibiting in-stent restenosis with arsenic trioxide drug-eluting stent: Enhancing contractile phenotype of vascular smooth muscle cells via YAP pathway.
Not available
S-EPMC7484501 | biostudies-literature
TranscriptomicsTranscription profiling of kidney from rats of SHR/Ola, BN and SHR-18 strains after being provided with drinking water with 1% or 0% sodium chloride
Four male SHR/Ola, BN and SHR-18 rats were fed a normal diet and sacrificed at 9 weeks of age. Four male SHR/Ola and SHR-18 rats at 8 weeks of age were fed 1% NaCl for one week and then sacrificed. Kidneys were removed and frozen in liquid nitrogen for all 20 animals. Total RNA was isolated, labelle...
ORGANISM(S): Rattus norvegicus 
2008-04-01 | E-MIMR-1122 | biostudies-arrayexpress
UnknownDJ4 Targets the Rho-Associated Protein Kinase Pathway and Attenuates Disease Progression in Preclinical Murine Models of Acute Myeloid Leukemia.
Not available
S-EPMC8508452 | biostudies-literature
UnknownHigh-dose isoniazid for TB with low-to-moderate isoniazid resistance after 1 week of treatment.
Not available
S-EPMC12096161 | biostudies-literature
TranscriptomicsBinding data for nine transcription factors for S. cerevisiae salt response
Complex biological processes are often regulated, at least in part, by the binding of transcription factors to their targets. Recently, considerable effort has been made to analyze the binding of relevant factors to the suite of targets they regulate, thereby generating a regulatory circuit map. H...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-20 | E-GEOD-15639 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis treated with silwet for varying time and high throughout haplotyping and single feature polymorphism markers in Arabidopsis
The study of natural genetic variation for plant disease resistance responses is a complementary approach to utilizing mutants to elucidate genetic pathways. While some key genes involved in pathways controlling disease resistance, and signaling intermediates such as salicylic acid (SA) and jasmoni...
ORGANISM(S): Arabidopsis thaliana 
2006-11-14 | E-TABM-60 | biostudies-arrayexpress
TranscriptomicsThe antimicrobial peptide-sensing system aps of Staphylococcus aureus
Staphylococcus aureus is a leading cause of hospital-associated infections. In addition, highly virulent strains of methicillin-resistant S. aureus (MRSA) are currently spreading outside health care settings. Survival in the human host is largely defined by the ability of S. aureus to resist mechani...
ORGANISM(S): Staphylococcus aureus 
2008-04-06 | E-GEOD-8400 | biostudies-arrayexpress
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