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UnknownMajor Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma.
Not available
S-EPMC5877802 | biostudies-literature
TranscriptomicsComparison of gene expression profile in RAG2+ B lineage cells from the small intestinal lamina propria and RAG2+ B lineage cells from the bone marrow
We used a RAG2-GFP reporter mouse to show that RAG+ B lineage cells can be found in the small intestinal lamina proria in normally-housed mice at weaning age. We used microarry expression analysis to compare the RAG2+ population in the gut to the RAG2+ B lineage population in the bone marrow. Microa...
ORGANISM(S): Mus musculus 
2013-07-12 | E-GEOD-48805 | biostudies-arrayexpress
TranscriptomicsHigh throughput sequencing of immunoglobulin (Ig) heavy (IgH) and light (IgL) chain repertoires
We used 454 sequencing to assess the repertoire of B cell subsets from bone marrow, spleen, and small intestinal lamina propria from two mouse strains. We used a RAG2-GFP reporter mouse strain (129Sve background) to isolate CD19+ RAG2+ B lineage cells from bone marrow and small intestinal lamina pro...
ORGANISM(S): Mus musculus 
2013-07-16 | E-GEOD-48870 | biostudies-arrayexpress
TranscriptomicsNuclear factor kappa B activation-induced anti-apoptosis renders HER2 positive cells drug resistant and accelerates tumor growth
Breast cancers with HER2 overexpression are sensitive to drugs targeting the receptor or its kinase activity. HER2-targeting drugs are initially effective against HER2- positive breast cancer, but resistance inevitably occurs. We previously found that nuclear factor kappa B is hyper-activated in the...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-52707 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine neonatal lung tissue from Carm1 knockouts and wild type controls
Coactivator associated arginine methyltransferase I (CARM1, also known as Protein aRginine MethylTransferase 4, or PRMT4) regulates gene expression by multiple mechanisms including methylation of histones and coactivation of steroid receptor transcription. Mice lacking CARM1 are smaller than their l...
ORGANISM(S): Mus musculus 
2010-07-07 | E-GEOD-21606 | biostudies-arrayexpress
UnknownGenomic profiling for clinical decision making in lymphoid neoplasms.
Not available
S-EPMC9837456 | biostudies-literature
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