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ProteomicsA multi-tissue longitudinal proteomics study to evaluate the suitability of post-mortem samples for pathophysiological research
Recent developments in liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS)-based proteomics have drastically increased analytical depth and sample throughput, establishing a robust tool for comprehensive system-wide analyses. Such analyses are instrumental in studying the pathophysi...
ORGANISM(S): Mus musculus (Mouse) 
2024-12-17 | PXD053048 | Pride
Post-mortem Dia Proteomics Cadaver 
ProteomicsThe extracellular matrix landscape identifies different etiologies behind bicuspid and tricuspid aortic valve degeneration
The molecular basis of aortic valve degeneration (AVD) is unclear. The extracellular matrix (ECM) of the valve is in dynamic reciprocity with its surrounding microenvironment and contains molecular traits of the pathophysiological processes. We compared abundances of ECM proteins from excised valve ...
ORGANISM(S): Homo sapiens (Human) 
2023-09-03 | PXD025002 | Pride
Ecm Lc-ms/ms Human Aortic valve degeneration Extracellular matrix 
TranscriptomicsAffymetrix SNP array data for various human ES cell lines
Human pluripotent stem cells commonly undergo adaptive changes during prolonged passaging in vitro. We have developed a new laminin-521 based method for self-renewal of human pluripotent stem cells. SNP6.0 array was used to assess genetic stability of several human ES cell lines cultured in the new ...
ORGANISM(S): Homo sapiens 
2013-12-19 | E-GEOD-53436 | biostudies-arrayexpress
ProteomicsEnhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics
We present a high-sensitivity SCP workflow named Chip-Tip, identifying >5000 proteins in individual HeLa cells
ORGANISM(S): Homo Sapiens 
PXD054944 |
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