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ModelsMachado2014 - Curcumin production pathway in Escherichia coli
Machado2014 - Curcumin production pathway in Escherichia coli This model is described in the article: A kinetic model for curcumin production in Escherichia coli. Machado D, Rodrigues LR, Rocha I. BioSystems 2014 Nov; 125: 16-21 Abstract: Curcumin is a natural compoun...
2024-09-02 | BIOMD0000000565 | BioModels
ProteomicsC. elegans as a model for inter-individual variation in metabolism
Fox BW, Ponomarova O, Lee YU, Zhang G, Giese EG, Walker M, Roberto NM, Na H, Reis-Rodrigues P, Curtis BJ, Kolodziej AR, Crombie TA, Zdraljevic S, Yilmaz LS, Andersen EC, Schroeder FC, Walhout AJM (2022) C. elegans as a model for inter-individual variation in metabolism
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2021-07-13 | MSV000087810 | MassIVE
TranscriptomicsImprinted expression of genes and small RNA is triggered by localized demethylation of the maternal genome in rice endosperm
We report that rice endosperm shows a specific hypomethylation of DNA in the maternal genome, preferring regions of high DNA accessibility. Maternally expressed imprinted genes are enriched for hypomethylation at putative promoter regions and transcriptional termini, and paternally expressed genes a...
ORGANISM(S): Oryza sativa 
2013-05-01 | E-GEOD-44898 | biostudies-arrayexpress
GenomicsLocal DNA hypomethylation activates genes in rice endosperm
Cytosine methylation silences transposable elements in plants, vertebrates and fungi, but also regulates gene expression1. Plant methylation is catalyzed by three families of enzymes, each with a preferred sequence context: CG, CHG (H = A, C or T) and CHH, with CHH methylation targeted by the RNA in...
ORGANISM(S): Oryza sativa 
2010-11-01 | E-GEOD-22591 | biostudies-arrayexpress
TranscriptomicsAnalysis of human enteroids and colonoids (3D organoid models from small intestine and colon) exposed to chemotherapy agent 5-fluorouracil (5FU) in a dose-repeated exposure across three doses (10,100 and 1000uM) and sampled at three points (24, 48 and 72h) since initial exposure. Organoids were obtained from healthy human tissues.
ADRs (adverse drug reactions) are one of the main reasons for treatment discontinuation or alterations in dose regimens in clinical settings. Chemotherapy-induced ADRs are common, especially gastrointestinal-induced ones. Within TransQST (transqst.org), one of the main goal is to improve the in vitr...
ORGANISM(S): Homo sapiens 
2021-09-09 | E-MTAB-9134 | biostudies-arrayexpress
GenomicsActive DNA demethylation in plant companion cells reinforces transposon methylation in gametes
The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes DNA demethylation prior to fertilization, but the targeting preferences and biological significance of this process remain unclear. Here, we show that active DNA demethylation mediated by the DEMETER DNA glycosylase acco...
ORGANISM(S): Arabidopsis thaliana 
2012-09-21 | E-GEOD-38935 | biostudies-arrayexpress
UnknownGenetic Diversity of Plasmodium vivax Cysteine-Rich Protective Antigen (PvCyRPA) in Field Isolates from Five Different Areas of the Brazilian Amazon.
Not available
S-EPMC8623135 | biostudies-literature
UnknownThe impact of a cash transfer programme on tuberculosis treatment success rate: a quasi-experimental study in Brazil.
Not available
S-EPMC6347926 | biostudies-literature
TranscriptomicsGene expression profiles of head and neck squamous cell carcinoma
Sage performed on microdissection of Head and Neck tumor, and Head and Neck normal tissue comparative analysis of gene expression profiles of head and neck squamous cell carcinoma and Head and Neck normal tissue
ORGANISM(S): Homo sapiens 
2008-09-30 | E-GEOD-11986 | biostudies-arrayexpress
UnknownPfkelch13 Plasmodium falciparum Mutations in Huambo, Angola.
Not available
S-EPMC9146480 | biostudies-literature
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