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TranscriptomicsTranscription profiling of mice tissues comparing microRNA-22 KO to wildtype
To explore the role of miR-22 targeting in different tissues in adult mice, we generated a miR-22 null mouse model and profiled expression in muscle, heart, liver, kidney and white adipose tissue.
ORGANISM(S): Mus musculus 
2014-03-06 | E-MTAB-2038 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice hearts comparing microRNA-22 overexpression to wildtype
To explore the role of miR-22 in the heart, we generated miR-22 null and transgenic mice. Cardiac transgenic overexpression of miR-22 in vivo led to cardiac hypertrophy that evolved into progressive dilated cardiomyopathy (DCM) in unstressed hearts. We found that miR-22 directly regulates two transc...
ORGANISM(S): Mus musculus 
2012-12-01 | E-MTAB-501 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse wild type or mir-155 deficient B cells after stimulation with LPS and IL4
Wild type or miR-155 deficient b cells from 5 individuals each were stimulated with LPS and IL4 for 24hs and profiled.
ORGANISM(S): Mus musculus 
2007-11-21 | E-MEXP-1325 | biostudies-arrayexpress
UnknownSingle-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.
Not available
S-EPMC10484789 | biostudies-literature
UnknownModeling early phenotypes of Parkinson's disease by age-induced midbrain-striatum assembloids.
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UnknownEmpagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC10957483 | biostudies-literature
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