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The in vivo effects of Ocoxin Oral solution (OOS) were evaluated on acute myeloid leukemia mice models. With that purpose RNA from 3 control untreated animals and 3 daily-OOS treated animals was purified and their gene expression profiles compared using the Affimetrix Transcriptome Analysis console....
ORGANISM(S): Homo sapiens 
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
The project is focused on the highly conserved sRNA scr5329 in Streptomyces coelicolor. A proteomics approach revealed that the sRNA regulates several metabolic enzymes, among them the Phosphoenolpyruvate-Carboxykinase (PEPCK), a key enzyme of the central carbon metabolism. The sRNA scr5239 promotes...
ORGANISM(S): Streptomyces coelicolor Bacteria 
2020-01-28 | PXD016811 | Pride
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