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GenomicsRegulation of Mediator-dependent transcriptional activation of Pol II(G) through TFII
Pol II(G) is a novel form of RNA polymerase II that contains a tightly associated Gdown1 polypeptide. Whereas Pol II suffices for robust activator-dependent transcription in the absence of Mediator, Pol II(G) is highly dependent upon Mediator in a biochemically defined in vitro system. However, the ...
ORGANISM(S): Homo sapiens 
2012-01-13 | E-GEOD-33128 | biostudies-arrayexpress
TranscriptomicsH3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation [HIT-Seq]
Histone modifications regulate chromatin-dependent processes, yet the mechanisms by which they contribute to specific outcomes remain unclear. H3K4me3 is a prominent histone mark that is associated with active genes and promotes transcription through interactions with effector proteins that include ...
ORGANISM(S): Mus musculus 
2013-03-02 | E-GEOD-43540 | biostudies-arrayexpress
GenomicsH3K4me3 Interactions with TAF3 Regulate Preinitiation Complex Assembly and Selective Gene Activation [ChIP-Seq]
Histone modifications regulate chromatin-dependent processes, yet the mechanisms by which they contribute to specific outcomes remain unclear. H3K4me3 is a prominent histone mark that is associated with active genes and promotes transcription through interactions with effector proteins that include ...
ORGANISM(S): Homo sapiens 
2013-03-02 | E-GEOD-43539 | biostudies-arrayexpress
Proteomics5HT - Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
we provide evidence for a new class of histone posttranslational modification (PTM): serotonylation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-04 | MSV000093567 | MassIVE
ProteomicsEstrogen Receptor Mutant Coregulator
Biotinylated 4xERE-containing DNA immobilized on streptavidin beads used to pulldown proteins recruited by unliganded WT ER-alpha versus Y537S, D538G, or ESR1-YAP1 fusion proteins from HeLa S3 human cell nuclear extracts.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-02-08 | MSV000080536 | MassIVE
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