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TranscriptomicsCombined gene expression and network analyses and the role of the RNAP II C-Terminal Domain in mitotic segregation
The C-terminal domain (CTD) of the largest subunit in DNA-dependent RNA polymerase II (RNAP II) is essential for mRNA syntheses, coordinating an astounding array of protein-protein interactions. In yeast, mutations that separate established functional units of the CTD result in pleiotrophic effects,...
ORGANISM(S): Saccharomyces cerevisiae 
2010-09-09 | E-GEOD-14342 | biostudies-arrayexpress
TranscriptomicsRegulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans
Constitutive overexpression of the Mdr1 efflux pump is an important mechanism of acquired drug resistance in the yeast Candida albicans. The zinc cluster transcription factor Mrr1 is a central regulator of MDR1 expression, but other transcription factors have also been implicated in MDR1 regulation....
ORGANISM(S): Candida albicans 
2011-07-01 | E-GEOD-23532 | biostudies-arrayexpress
TranscriptomicsComparative genomics of Steinernema reveals deeply conserved regulatory networks in nematodes
Parasitism is a major ecological niche for a variety of nematodes. Multiple nematode lineages have specialized as pathogens, including deadly parasites of insects that are used in biological control. We have sequenced and analyzed the draft genomes and transcriptomes of the entomopathogenic nematode...
ORGANISM(S): Caenorhabditis elegans 
2015-06-05 | E-GEOD-68588 | biostudies-arrayexpress
UnknownIdentification of nine new susceptibility loci for endometrial cancer.
Not available
S-EPMC6085317 | biostudies-literature
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