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UnknownCapecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04.
Not available
S-EPMC4050205 | biostudies-literature
UnknownEpigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeutics Research Group.
Not available
S-EPMC3438233 | biostudies-literature
GenomicsGenomic Profiling of HMGN1 Reveals an Association with Chromatin at Regulatory Regions
High mobility group (HMG) proteins interact with other architectural proteins to regulate chromatin structure. We performed genome-wide mapping experiments to examine the distribution of HMGN1 across the human genome. We discovered that HMGN1 proteins are enriched at regulatory regions such as DNas...
ORGANISM(S): Homo sapiens 
2010-11-30 | E-GEOD-25674 | biostudies-arrayexpress
TranscriptomicsGene expression profile of WT and TAK1 KO livers.
The effect of ablation of Tak1 gene in the liver was characterized. RNA was extracted from 1-month-old WT and hepatocyte specific TAK1-deleted mice
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-51962 | biostudies-arrayexpress
ProteomicsMetabolite glues as a means of purine sensing and chemotherapeutic response
FLAG immunoprecipitation of NUDT5 WT and Y74F, and Strep-FLAG sequential immunoprecipitation of PPAT-NUDT5 complexes from HEK293T cells lentivirally expressing tagged constructs
ORGANISM(S): Homo sapiens (Human) 
2026-05-22 | PXD077951 | Pride
Molecular glue Purine metabolism 
TranscriptomicsMyeloid derived suppressor cells enhance stemness of cancer cells by inducing miRNA101 and suppressing the corepressor CtBP2
The work identifies an immune associated cellular, molecular and clinical network involving MDSCs-microRNA101-CtBP2-stem cell core genes, which extrinsically controls cancer stemness and impacts patient outcome. Primary ovarian cancer cells (5 x105) were co-cultured with freshly sorted ovarian cance...
ORGANISM(S): Homo sapiens 
2013-08-23 | E-GEOD-50082 | biostudies-arrayexpress
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