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TranscriptomicsIn vitro carcinogenicity testing with Balb/c 3T3 Cells treated with various chemical carcinogens
Background: Information on the carcinogenic potential of chemicals is only availably for High Production Volume products. There is however, a pressing need for alternative methods allowing for the chronic toxicity of substances, including carcinogenicity, to be detected earlier and more reliably. He...
ORGANISM(S): Mus musculus 
2010-10-02 | E-GEOD-22180 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human NSCLC tumor progression
To identify genes associated with lung cancer progression, we examined gene expression profiles of tumor cells from 20 patients with primary, untreated non-small cell lung cancer (10 adenocarcinomas (AC) and 10 squamous cell carcinomas (SCC)) in comparison to lung tissue of 23 patients with stage II...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7880 | biostudies-arrayexpress
TranscriptomicsExpression data from SP and non-SP sorted anti-EpCAM treated A549 cells
Targeted therapies against cancer stem cells, which are enriched in side populations (SP), involves interruption of Wnt-signalling. Furthermore, EpCAM is a SP marker and modulator of Wnt-signalling. Therefore, the effects of an anti-EpCAM treatment on SP-cells and WNT/β-catenin signalling was studi...
ORGANISM(S): Homo sapiens 
2012-08-07 | E-GEOD-31315 | biostudies-arrayexpress
UnknownTranscription profiling of human NSCLC tumor progression
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-7880 | biostudies-other
TranscriptomicsExpression data from SP and non-SP sorted anti-EpCAM treated A2C12 cells
Targeted therapies against cancer stem cells which are enriched in side populations (SP) involves interruption of Wnt-signalling. Furthermore, EpCAM is a SP marker and modulator of Wnt-signalling. Therefore, the effects of an anti-EpCAM treatment on SP-cells and WNT/M-NM-2-catenin signalling was stu...
ORGANISM(S): Mus musculus 
2012-08-07 | E-GEOD-31246 | biostudies-arrayexpress
UnknownExpression data from SP and non-SP sorted anti-EpCAM treated A549 cells
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-31315 | biostudies-other
UnknownDysbindin is a potent inducer of RhoA–SRF-mediated cardiomyocyte hypertrophy
Not available
S-JCBD-201303052 | bioimages
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