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TranscriptomicsWhole genome expression signature of SWCNT and MWCNT vs. asbestos subchronic exposures to human pleural mesothelial cells
Malignant mesothelioma is one of the most aggressive forms of cancer known. Recent studies have shown that carbon nanotubes (CNTs) are biopersistent and induce mesothelioma in animals, but the underlying mechanisms are not known. Here, we investigate the effect of long-term exposure to CNTs on the a...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-48855 | biostudies-arrayexpress
UnknownSOX2Mediates Carbon Nanotube-Induced Fibrogenesis and Fibroblast Stem Cell Acquisition.
Not available
S-EPMC8215839 | biostudies-literature
TranscriptomicsWhole genome expression profile of lung epithelial cells following chronic arsenic exposure
This study chronically exposed human lung epithelial BEAS-2B cells to low-dose arsenic trioxide in vitro to elucidate cancer promoting gene signaling networks (GSNs) associated with As-transformed (B-As) cells. Following a six month exposure, exposed cells were assessed for enhanced cell proliferat...
ORGANISM(S): Homo sapiens 
2012-09-26 | E-GEOD-33520 | biostudies-arrayexpress
TranscriptomicsWhole genome profile of SWNCT and MWCNT vs. asbestos subchronic exposures to human small airway epithelial cells
Recent in vivo studies reported that inhaled carbon nanotube distribute in the alveolar region resulting in an acute inflammation, progressive fibrotic response and particle accumulation at the bronchoalveolar junction with low clearance. With similar biopersistence and shape as asbestos, a known l...
ORGANISM(S): Homo sapiens 
2013-07-22 | E-GEOD-41178 | biostudies-arrayexpress
UnknownThe SOX9-Aldehyde Dehydrogenase Axis Determines Resistance to Chemotherapy in Non-Small-Cell Lung Cancer.
Not available
S-EPMC6944474 | biostudies-literature
UnknownPredicting Nanotube Fibrogenicity through Stem Cell-Mediated Fibroblast Focus and Spheroid Formation.
Not available
S-EPMC6298034 | biostudies-literature
UnknownIron Oxide Nanoparticle-Induced Neoplastic-Like Cell Transformation in Vitro Is Reduced with a Protective Amorphous Silica Coating.
Not available
S-EPMC7457399 | biostudies-literature
UnknownSOX9 Regulates Cancer Stem-Like Properties and Metastatic Potential of Single-Walled Carbon Nanotube-Exposed Cells.
Not available
S-EPMC5599589 | biostudies-literature
UnknownSubstrate Stiffness-Dependent Carbon Nanotube-Induced Lung Fibrogenesis.
Not available
S-EPMC6724206 | biostudies-literature
UnknownSynthesis and Evaluation of the α-D-/α-L-Rhamnosyl and Amicetosyl Digitoxigenin Oligomers as Anti-tumor Agents.
Not available
S-EPMC3108330 | biostudies-literature
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