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SARS-CoV-2 extensively N-glycosylates its spike proteins, which are essential for host cell invasion, target of vaccines, and immunotherapy. These N-glycans are predicted to help mediate spike binding to the host receptor. We investigated the essentiality of the host N-glycosylation pathway and viru...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2022-02-04 | PXD026431 | Pride
The mineralocorticoid aldosterone mainly produced by the adrenal gland is essential for life but an abnormal excessive secretion causes severe pathological effects including hypertension and target organ injury in the heart and kidney. The aim of this study was to determine the gene regulatory netwo...
ORGANISM(S): Rattus norvegicus 
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