Sort   by:  
 Page size 
ProteomicsImpairment of autophagic flux by combined EGFR and ROCK inhibition leads to triple-negative breast cancer cell death
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with very limited therapeutic options. We have recently shown that the combined inhibition of EGFR and ROCK in TNBC cells results in cell cycle arrest and ultimately cell death. However, the underlying mechanisms by which...
ORGANISM(S): Homo sapiens (Human) 
2019-12-04 | PXD013821 | Pride
Autophagy Triple-negative breast cancer Proteomics Label-free Rock Targeted therapy Egfr 
ProteomicsProteomic profiling of breast cancer-derived extracellular vesicles
In-depth (phospho)proteome characterization of breast cancer derived extracellular vesicles (EVs).
ORGANISM(S): Homo sapiens (Human) 
2019-10-24 | PXD012162 | Pride
Breast cancer Extracellular vesicles 
UnknownFerritin heavy chain supports stability and function of the regulatory T cell lineage
Regulatory T (TREG) cells develop via a program orchestrated by the transcription factor forkhead box protein P3 (FOXP3). Maintenance of the TREG cell lineage relies on sustained FOXP3 transcription via a mechanism involving demethylation of cytosine-phosphate-guanine (CpG)-rich elements at conserve...
S-SCDT-10_1038-S44318-024-00064-X | biostudies-other
Sort   by:  
 Page size