Sort   by:  
 Page size 
ProteomicsRevealing the dynamic allosteric changes required for formation of the cysteine synthase complex by hydrogen-deuterium exchange mass spectrometry
CysE and CysK, the last two enzymes of the cysteine biosynthetic pathway, engage in a bienzyme complex, cysteine synthase (CS), with yet incompletely characterized three-dimensional structure and regulatory function. Being absent in mammals, the two enzymes and their complex are attractive targets f...
ORGANISM(S): Escherichia coli 
2021-06-07 | PXD025300 | Pride
Cysteine biosynthesis Allosteric regulation E. coli Synapt g2-si Bienzyme complex Hydrogen deuterium exchange (hdx-ms) Protein-protein interactions Cysteine synthase 
TranscriptomicsPhase I study of Veliparib in combination with Cisplatin and Vinorelbine for patients with advanced triple-negative breast cancer (TNBC) and/or BRCA mutation-associated breast cancer
PURPOSE: Preclinically, cisplatin is synergistic with vinorelbine and the poly(ADP-ribose) polymerase (PARP) inhibitor veliparib, and has anti-neoplastic activity in TNBC and BRCA mutation-associated breast cancer. This phase I study assessed veliparib with cisplatin and vinorelbine. PATIENTS AND M...
ORGANISM(S): Homo sapiens 
2015-09-09 | E-GEOD-72795 | biostudies-arrayexpress
UnknownRisk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study.
Not available
S-EPMC8336996 | biostudies-literature
UnknownDifference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study.
Not available
S-EPMC8270522 | biostudies-literature
Sort   by:  
 Page size