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TranscriptomicsThe transcriptional modulator H2AFY marks Huntington's disease activity in men and mice
To accelerate the development of disease-modifying therapeutics for Huntington’s disease (HD), a dynamic biomarker of disease activity and treatment response is critically needed. Venous cellular whole blood from 8 patients with Huntington's disease (HD) and 6 control subjects were collected in PAXg...
ORGANISM(S): Homo sapiens 
2011-09-01 | E-GEOD-24250 | biostudies-arrayexpress
TranscriptomicsHuman blood expression for Huntington's disease versus control
Affymetrix U133A expression levels for 12 symptomatic and 5 presymptomatic Huntington's disease patients versus 14 healthy controls. Keywords: other
ORGANISM(S): Homo sapiens 
2005-09-13 | E-GEOD-1751 | biostudies-arrayexpress
UnknownGenome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.
Not available
S-EPMC1182457 | biostudies-literature
UnknownA futility study of minocycline in Huntington's disease.
Not available
S-EPMC8801051 | biostudies-literature
UnknownClinical impairment in premanifest and early Huntington's disease is associated with regionally specific atrophy.
Not available
S-EPMC6869979 | biostudies-literature
TranscriptomicsId proteins synchronize stemness and anchorage to the niche of neural stem cells
Stem cell functions require activation of stem cell-intrinsic transcriptional programs as well as intimate extracellular interactions with a niche microenvironment. How the core pluripotency transcriptional machinery controls residency of stem cells in the niche microenvironment is unknown. Here we ...
ORGANISM(S): Mus musculus 
2012-03-15 | E-GEOD-36488 | biostudies-arrayexpress
UnknownA randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease.
Not available
S-EPMC5224719 | biostudies-literature
UnknownAlzheimer-Related Cerebrovascular Disease in Down Syndrome.
Not available
S-EPMC7729262 | biostudies-literature
UnknownWHODAS 2.0 in prodromal Huntington disease: measures of functioning in neuropsychiatric disease.
Not available
S-EPMC4350592 | biostudies-literature
TranscriptomicsTranscription profiling timecourse of aging human myotubes cultured in low or high glucose medium
Aging of skeletal muscle tissue is characterized by loss of metabolic and contractile competence. It is thought that this phenomenon is driven via extrinsic and intrinsic factors. In order to identify age-dependent changes intrinsic to the muscle cell, microarray transcriptional profiles and measure...
ORGANISM(S): Homo sapiens 
2007-07-19 | E-GEOD-1144 | biostudies-arrayexpress
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