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TranscriptomicsAmplified genes are not necessarily over expressed, they can be unchanged or down regulated in cervical cancer cell lines [expression array data]
Several copy number altered regions (CNA) have been identified in the genome of cervical cancer, especially amplifications of 3q and 5p. However, the contribution of those alterations to cervical carcinogenesis is still a matter of debate, since genome-wide, there is a lack of correlation between CN...
ORGANISM(S): Homo sapiens 
2011-07-31 | E-GEOD-29216 | biostudies-arrayexpress
ProteomicsProteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature
The ovarian microenvironment becomes fibrotic and stiff with age due in part to increased stromal collagen and decreased hyaluronan. However, the extracellular matrix (ECM) is a complex network of hundreds of proteins, glycoproteins and glycans which are highly tissue specific and undergo pronounced...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-04-24 | MSV000091790 | MassIVE
UnknownSignificant increase of firework induced eye injuries in Germany and The Netherlands- are we doing enough to protect minors and bystanders?
Not available
S-EPMC12095323 | biostudies-literature
TranscriptomicsNon-Replicating Mycobacterium tuberculosis Elicits a Reduced Infectivity Profile with Corresponding Modifications to the Cell Wall and Extracellular Matrix
A key feature of Mycobacterium tuberculosis is its ability to become dormant in the host. Little is known of the mechanisms by which these bacilli are able to persist in this state. Therefore, the focus of this study was to emulate environmental conditions encountered by M. tuberculosis in the granu...
ORGANISM(S): Mycobacterium tuberculosis 
2016-11-14 | E-BUGS-142 | biostudies-arrayexpress
ProteomicsMetaproteomic study about diet-induced effects on the gut microbiota of patients affected by Crohn's disease
Metaproteomic study on fecal samples collected from Crohn's Disease (CD) patients and some Household Healthy Controls (HHC) during an eight week Lof Fat/High fiber diet intervention. Stoo sampling was performed at baseline (V1), week 8 (V2) and week 36 (V3). Protein Identification and quantitation ...
ORGANISM(S): Bacteria Homo Sapiens (ncbitaxon:9606) 
2024-02-01 | MSV000093975 | MassIVE
TranscriptomicsEarly transcriptional changes in Medicago truncatula upon Nod factor treatment
This experiment was part of a larger study to elucidate the early effects of Nod factor treatment on the Medicago truncatula phosphoproteome, transcriptome and metabolome in wildtype and two mutants. In this experiment, RNA-Seq was used to measure transcriptional changes in plant roots treated +/- N...
ORGANISM(S): Medicago truncatula 
2013-02-13 | E-MTAB-5064 | biostudies-arrayexpress
TranscriptomicsGGI: a potential predictor of relapse for endocrine-treated breast cancer patients in the BIG 1-98 trial
Background: We have previously shown that the Gene expression Grade Index (GGI) was able to identify two subtypes of estrogen receptor (ER)-positive tumors that were associated with statistically distinct clinical outcomes in both untreated and tamoxifen-treated patients. Here, we aim to investigate...
ORGANISM(S): Homo sapiens 
2009-07-09 | E-GEOD-16391 | biostudies-arrayexpress
TranscriptomicsRNA-seq of in vitro-generated murine T helper 17 cells
T helper (Th) 17 cells form a T cell subset which is crucial to maintain immunity against extracellular bacteria and fungi at epithelial barriers, but Th17 cells are also enriched at sites of inflammation in autoimmune disease. These sites are commonly characterised by adverse environmental conditio...
ORGANISM(S): Mus musculus 
2017-06-14 | E-MTAB-5692 | biostudies-arrayexpress
TranscriptomicsIGR_GLIOMA_STUDY_SP
Glioma study (gene expression and CGH): Brain tumours are the most common solid tumors in children and have the highest mortality rate of all solid pediatric tumours. Despite advances in multimodality therapy, children with high-grade gliomas invariably have an Overall Survival (OS) around 20% at 5 ...
ORGANISM(S): Homo sapiens 
2012-02-22 | E-TABM-1107 | biostudies-arrayexpress
UnknownPotassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery: The TIGHT K Randomized Clinical Trial.
Not available
S-EPMC11366075 | biostudies-literature
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