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TranscriptomicsTranscription profiling of human ovarian carcinomas
Unsupervised hierarchical clustering of ovarian cell lines and ovarian cancers. Cell lines were not co-clustered with the tumor specimens, because these cell lines have a very prominent proliferation cluster (Perou et al., 1999; Ross et al., 2000) that significantly influences the clustering of the ...
ORGANISM(S): Homo sapiens 
2006-06-06 | E-SMDB-2253 | biostudies-arrayexpress
TranscriptomicsOvarian cancers
Schaner M., et al.; Mol Biol Cell. 2003 Nov;14(11):4376-86. Figure 1 Unsupervised hierarchical clustering of ovarian cell lines and ovarian cancers. Cell lines were not co-clustered with the tumor specimens, because these cell lines have a very prominent proliferation cluster (Perou et al., 1999; Ro...
ORGANISM(S): Homo sapiens 
2006-02-24 | E-GEOD-4198 | biostudies-arrayexpress
MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
TranscriptomicsTranscription profiling of chicken intestinal intraepithelial lymphocytes following oral feeding of carvacrol cinnamaldehyde or capsicum oleoresin
One day-old broilers (Ross/Ross, Longenecker's Hatchery, Elizabethtown, PA) were housed in Petersime starter brooder units and randomly assigned to 4 groups (5 birds/group). Carvacrol (Nature Chemicals, Hamburg, Germany) and cinnamaldehyde (Alys Technologies SA, Bussigny-près-Lausanne, Switzerland) ...
ORGANISM(S): Gallus gallus 
2009-06-02 | E-MEXP-2204 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing data of zebrafish lymphatic and venous endothelial cells at different developmental stages (36 hpf, 48 hpf, 120 hpf (5 dpf) and 168 hpf (7 dpf))
This dataset contains single-cell RNA sequencing (scRNA-seq) profiles of zebrafish venous and lymphatic endothelial cells across development. Endothelial cells were isolated by FACS from transgenic zebrafish embryos and larvae at 36 hpf, 48 hpf, 5 dpf (120 hpf), and 7 dpf (168 hpf) using endothelial...
ORGANISM(S): Danio rerio 
2026-09-28 | E-MTAB-16797 | biostudies-arrayexpress
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
TranscriptomicsHuman mammary epithelium and breast cancer
Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. cDNA microarrays and a clustering algorithm were used to identify patterns of gene expression in human mammary epithelial cells growing in culture and in primary human breast tumors. Clusters of coexpressed ge...
ORGANISM(S): Homo sapiens 
2002-06-27 | E-GEOD-53 | biostudies-arrayexpress
TranscriptomicsMolecular portraits of human breast tumors
Set of 65 surgical specimens of human breast tumors from 42 different individuals, using complementary DNA microarrays representing 8,102 human genes. Gene expression variation patterns within this set provided a distinctive molecular portrait of each tumor. Twenty of the tumors were sampled twice, ...
ORGANISM(S): Homo sapiens 
2002-06-27 | E-GEOD-61 | biostudies-arrayexpress
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
TranscriptomicsProbing the endosperm gene expression landscape in Brassica napus
In species with exalbuminous seeds such as crucifer oilseeds and legumes, the endosperm is eventually consumed and its space occupied by the embryo during seed development. However, the main constituent of the early developing seed is the liquid endosperm, and most of the carbon resources for the en...
ORGANISM(S): Brassica napus 
2010-05-18 | E-GEOD-14766 | biostudies-arrayexpress
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