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TranscriptomicsDNA methylation array of human purified intestinal epithelial samples and organoids from paediatric and foetal small and large intestine
Human intestinal epithelial organoids (IEO) culture models are rapidly emerging as novel experimental tools to investigate fundamental aspects of intestinal epithelial (patho)physiology. Cellular source and culture protocols vary between different IEO models and reliable markers for their characteri...
ORGANISM(S): Homo sapiens 
2017-10-31 | E-MTAB-4957 | biostudies-arrayexpress
GenomicsMETABRIC: Data from Pereira et al (2016), The somatic mutation profiles of 2433 breast cancers refine their genomic and transcriptomic landscapes. Nat Comms 7.
The genomic landscape of breast cancer is complex, and inter- and intra-tumour heterogeneity are important challenges in treating the disease. In this study, we sequence 173 genes in 2433 primary breast tumours that have copy number aberration (CNA), gene expression, and long-term clinical follow-u...
EGAS00001001753 | EGA
GenomicsWhole-Genome and Exome Sequencing in clear-cell Renal Cell Carcinoma (ccRCC)

Study to evaluate the molecular genetics of ccRCC through integrative analyses of tumors and tumorgrafts using multiple platforms in clinically annotated samples. Genome and exome data for patients giving consent to have the information available on a public, secure, database is being submitted.<...

phs000491.v1.p1 | EGA
GenomicsA Comprehensive Catalogue of Somatic Mutations from a Human Cancer Genome
We have carried out complete sequencing of the genome of the human male maligant melanoma cell line COLO-829 using the Illumina Genome Analyzer II. We generated a sequencing library with a median insert size of ~200 bp following random fragmentation and gel fractionation of the genomic DNA. We seque...
EGAS00000000052 | EGA
ProteomicsAKT Inhibition Promotes Non-autonomous Cancer Cell Survival [Antibody Arrays (L-507)]
Small-molecule inhibitors of AKT signaling are being in evaluated in patients with various cancer types, but have so far proven therapeutically disappointing for reasons that remain unclear. Here, we treat cancer cells with sub-therapeutic doses of Akti-1/2, an allosteric small molecule AKT inhibito...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-71892 | biostudies-arrayexpress
ProteomicsAKT Inhibition Promotes Non-autonomous Cancer Cell Survival [Antibody Arrays (L-493)]
Small-molecule inhibitors of AKT signaling are being in evaluated in patients with various cancer types, but have so far proven therapeutically disappointing for reasons that remain unclear. Here, we treat cancer cells with sub-therapeutic doses of Akti-1/2, an allosteric small molecule AKT inhibito...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-71891 | biostudies-arrayexpress
Genomicsena-DATASET-CRUK-CI-16-05-2016-12:25:56:672-139 - samples
Targeted sequencing of 173 genes in 2433 primary breast tumours. Data includes 2433 tumour samples, 523 adjacent normal (breast) samples and 127 blood samples. Libraries were prepared with Illumina's Nextera custom enrichment kit targetting all the exons of the most frequently mutated breast cance...
EGAD00001002115 | EGA
GenomicsEGAD00000000055
COLO-829 is a publicly available immortal cancer cell line and COLO-829BL is a lymphoblastoid cell line derived from the same patient
EGAD00000000055 | EGA
GenomicsSequencing data for oesophageal and related samples - OCCAMS 496 release - samples
Data from 496 OCCAMS (Oesophageal Cancer Clinical And Molecular Stratification) cases. WGS BAM files 496x oesophageal adenocarcinoma samples 496x normal samples
EGAD00001007785 | EGA
UnknownAnaesthesia Choice for Creation of Arteriovenous Fistula (ACCess) study protocol : a randomised controlled trial comparing primary unassisted patency at 1 year of primary arteriovenous fistulae created under regional compared to local anaesthesia.
Not available
S-EPMC8704953 | biostudies-literature
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