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UnknownMsrR, a putative cell envelope-associated element involved in Staphylococcus aureus sarA attenuation.
Not available
S-EPMC166063 | biostudies-literature
TranscriptomicsRadiotherapy-induced miR expression influences breast cancer recurrence formation.
The act of surgery strongly stimulated breast cancer cell growth in mice. Local irradiation of wounded breast efficiently prevented wounded-induced breast cancer cell growth. These modifications were linked to miR modulation both in human specimens and in the mouse model, in vivo. The most significa...
ORGANISM(S): Homo sapiens 
2017-01-03 | E-MTAB-1562 | biostudies-arrayexpress
TranscriptomicsExpression data from untreated and ATP treated AML blasts
In the present study, we investigated whether, and to what extent, P2Rs and their ligands are involved in the regulation of AML cells. Our findings show that AML blasts express several receptors belonging to the P2X and P2Y family. Although different samples respond differently to ATP and UTP stimul...
ORGANISM(S): Homo sapiens 
2012-02-25 | E-GEOD-30903 | biostudies-arrayexpress
UnknownNatural History, Phenotypic Spectrum, and Discriminative Features of Multisystemic RFC1 Disease.
Not available
S-EPMC8055326 | biostudies-literature
TranscriptomicsTranscription profiling of human CD34+ cells and treatment with UTP and CXCL12
Homing and engraftment of hematopoietic stem cells (HSCs) to the bone marrow (BM) involve a complex interplay between chemokines, cytokines, and non-peptide molecules. Extracellular nucleotides and their cognate P2 receptors are emerging as key-factors of inflammation and related chemotactic respons...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5168 | biostudies-arrayexpress
TranscriptomicsIncomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
Human induced pluripotent stem (iPS) cells are remarkably similar to embryonic stem (ES) cells, but recent reports indicate that there may be important differences between them. We carried out a systematic comparison of human iPS cells generated from hepatocytes (representative of endoderm), skin fi...
ORGANISM(S): Homo sapiens 
2011-04-17 | E-GEOD-23034 | biostudies-arrayexpress
UnknownChronic myeloid leukemia management at the time of the COVID-19 pandemic in Italy. A campus CML survey.
Not available
S-EPMC7301058 | biostudies-literature
TranscriptomicsA20 IN MARGINAL ZONE LYMPHOMAS
Unique and shared cytogenetic abnormalities have been documented for marginal zone lymphomas (MZLs) arising at different sites. Recently, homozygous deletions of the chromosomal band 6q23, involving the tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) gene, a negative regulator of NF-kap...
ORGANISM(S): Homo sapiens 
2009-04-01 | E-GEOD-13989 | biostudies-arrayexpress
GenomicsHigh density copy number analysis and whole exome sequencing of chronic lymphocytic leukemia

The pathogenesis of chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is still largely unknown since the full spectrum of genetic lesions that are present in the CLL genome, and therefore the number and identity of dysregulated cellular pathways, have not been iden...

phs000364.v1.p1 | EGA
TranscriptomicshMSC ATP treatment
Nucleotides triphosphates are extracellular messengers binding to specific plasma membrane receptors (P2Rs) that modulate responses as different as proliferation, differentiation, migration or cell death on several cell types including hematopoietic stem cells. Little and controversial information i...
ORGANISM(S): Homo sapiens 
2013-04-11 | E-GEOD-14566 | biostudies-arrayexpress
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