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ProteomicsCharacterization of human aging and Parkinson’s disease pre-frontal cortex by multi-omics: a glycomics, proteomics study.
This study identifies the age and PD related changes in glycans (HS and CS disaccharides) and proteomics in human aging and Parkinson’s disease. We analyzed the prefrontal cortex for changes in HS, CS and proteomic signatures in young versus aged as well as aged and PD in two cohorts. These studies ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-16 | PXD018736 | Pride
Chondroitin sulfate Mass spectrometry Reverse phase Hilic-wax Multi-omics Label-free proteomics Pre-frontal cortex Heparan sulfate Lc-msms. Proteomic Parkinson’s disease Glycomic Aging 
ProteomicsSpatial Proteomics of a Human Brain Tumour at 40 µm resolution
The spatial organisation of Cellular protein expression profiles within tissues determines cellular function and are key to understanding disease pathology. To define molecular phenotypes in the spatial context of tissue, there is a need for unbiased, quantitative technology capable of mapping prote...
ORGANISM(S): Homo sapiens (Human) 
2023-10-10 | PXD044714 | Pride
Spatial proteomics Laser capture microdissection Roteomics 
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