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ProteomicsTranscriptomic and Proteomic Insight into the Mechanism of Cyclooctasulfur- versus Thiosulfate-Oxidation by the Chemolithoautotroph Sulfurimonas denitrificans
Chemoautotrophic bacteria belonging to the genus Sulfurimonas in the class Campylobacteria (formerly classified as Epsilonproteobacteria) play a key role in the sulfur cycle in a variety of oxygen-deficient or –limited and sulfide-rich marine and terrestrial environments. Previously, they were ident...
ORGANISM(S): Sulfurimonas denitrificans 
2019-07-22 | PXD009127 | Pride
Sulfur Campylobacteria Proteomics Oxidation Epsilonproteobacteria 
TranscriptomicsHPMCs treated with TNFalpha and IL-17A
Human mesothelial peritoneal cells from high grade serous ovarian carcinoma patients were subjected to TNFalpha, IL17-A and combination treatment.
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-13497 | biostudies-arrayexpress
TranscriptomicsscRNAseq of human omentum from high grade serous ovarian carcinoma patients, enriched for mesothelial cells
scRNAseq of HPMCs isolated ex vivo from 3 Patients. Targeted scRNASeq was applied using BD onco Panel with a additional genes. Purpose of the experiment was to characterize HPMC phenotype ex vivo and compare with the phenotype observed in RNAseq of HPMCs treated with IL17A and TNF.
ORGANISM(S): Homo sapiens 
2024-12-31 | E-MTAB-13498 | biostudies-arrayexpress
ProteomicsProtein Interactions of 7 MLL-fusion Proteins
MLL-fusions represent a large group of leukemia drivers, whose diversity originates from the vast molecular heterogeneity of C-terminal fusion partners of MLL protein. While studies of selected MLL-fusions have revealed critical molecular pathways, unifying mechanisms across all MLL-fusions remain p...
ORGANISM(S): Homo sapiens (Human) 
2018-05-25 | PXD009338 | Pride
Mll-fusion Leukemia Human 
MetabolomicsMonocolonization with Bacteroides thetaiotaomicron exerts region-specific effects on Alzheimer’s disease-related traits in the murine brain

Bacteroides thetaiotaomicron (B. theta) dominates the gut microbiome of most mammals. This strictly anaerobic gut symbiont colonizes the mucus layer of host intestinal epithelial cells in both healthy and diseased conditions. Reduced neuronal and vagal afferent innervation observed in ge...

2025-12-15 | MTBLS12896 | MetaboLights
ProteomicsDYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer
Highly malignant pancreatic ductal adenocarcinoma (PDAC) is characterized by an abundant immunosuppressive and fibrotic tumor microenvironment (TME). Future therapeutic attempts therefore demand targeting of both compartments in order to be effective. We show here that Dual Specificity and Tyrosine...
ORGANISM(S): Mus Musculus 
2024-01-02 | MSV000093747 | MassIVE
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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