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TranscriptomicsUnderstanding the role of Shoc2 protein in spatio-temporal regulation of extracellular signal-regulated kinase (ERK1/2) cascade
This study was designed to understanding changes in RNA transcription in cells depleted of Shoc2 scaffold. 2 samples were analyzed (3 replicates for each sample were included). Cos1 is a control sample.
ORGANISM(S): Chlorocebus sabaeus 
2016-01-15 | E-GEOD-67063 | biostudies-arrayexpress
TranscriptomicsGene regulation in denervated hairy skin of the adult rat
This study aimed to quantify the regulation of transcripts in the hairy skin of the back of adult rats in the condition of loss of sensory and autonomic (sympathetic) innervation (i.e., denervated). Denervated skin has reduced wound healing capacity, reduced proliferation of epidermal progenitor cel...
ORGANISM(S): Rattus norvegicus 
2014-04-08 | E-GEOD-54356 | biostudies-arrayexpress
TranscriptomicsGene expression responses to chronic low dose arsenite exposure
Arsenic (As) exposure is a significant worldwide environmental health concern. Low dose, chronic arsenic exposure has been associated with higher risk of skin, lung, and bladder cancer, as well as cardiovascular disease and diabetes. While arsenic-induced biological changes play a role in disease p...
ORGANISM(S): Homo sapiens 
2015-05-05 | E-GEOD-60760 | biostudies-arrayexpress
TranscriptomicsPrenatal Arsenic Exposure Alters Gene Expression in the Adult Liver to a Proinflammatory State Contributing to Accelerated Atherosclerosis
Developmental exposures play a role in adult onset chronic disease. The mechanisms by which environmental toxicants alter developmental processes predisposing individuals to chronic disease are not understood. arsenic exposure via drinking water causes cancer and cardiovascular disease. Transplacent...
ORGANISM(S): Mus musculus 
2012-06-21 | E-GEOD-30783 | biostudies-arrayexpress
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