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ProteomicsA heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients
Organelles like lysosomes and synaptic vesicles are acidified by V-ATPases, which consist of a cytosolically-oriented V1 complex that hydrolyzes ATP and a membrane-embedded VO complex that pumps protons. In yeast, V1-VO association is facilitated by the RAVE complex, but how higher eukaryotes assemb...
ORGANISM(S): Homo sapiens (Human) 
2025-05-20 | PXD064067 | Pride
Cx-ms Affinity purification 
GenomicsAn alternative pluripotent state confers interspecies chimaeric competency [WGBS]
In this study, we show that by simple modulation of extrinsic signaling pathways, a new class of pluripotent stem cells, referred to as region selective epiblast stem cells (rsEpiSCs), could be efficiently derived from different stages of the early embryo. rsEpiSCs share features of primed pluripote...
ORGANISM(S): Mus musculus 
2015-05-06 | E-GEOD-63568 | biostudies-arrayexpress
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