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UnknownROW1 maintains quiescent centre identity by confining WOX5 expression to specific cells.
Not available
S-EPMC4316744 | biostudies-literature
UnknownBARD1 may be renamed ROW1 because it functions mainly as a REPRESSOR OF WUSCHEL1.
Not available
S-EPMC2634073 | biostudies-literature
ProteomicsQuantitative Analysis of Ustilago maydis Secretome in Wild-Type and Δrow1 Strains
In this project, we conducted a quantitative analysis of secreted proteins during the initial stages of the pathogenic program in Ustilago maydis. We utilized the AB33 strain, which contains the compatible bE2/bW1 genes controlled by the nitrate-inducible nar1 promoter. Consequently, in nitrogen-ric...
ORGANISM(S): Ustilago maydis (Smut fungus) 
2024-04-20 | PXD047174 | Pride
Ustilago maydis Quantitative analysis Row1 Secretome 
TranscriptomicsmiRNA expression profiling of NB4 control cells versus NB4 cells treated with SAHA (Vorinostat)
For a long time, the BARD1 (BRCA1-associated RING domain 1) protein has been considered as a BRCA1 (BReast Cancer susceptibility gene 1, early onset) interactor, and tumor suppressor mutated in breast and ovarian cancers. Despite its functions in a stable heterodimer with BRCA1, there is increasing ...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-37374 | biostudies-arrayexpress
TranscriptomicsSpt6 Levels are Modulated by PAAF1 and 26S Proteasome to Regulate the HIV-1 LTR and a Subset of Cellular Genes involved in Cancer.
Effect of PAAF1 and Spt6 knock-down on gene expression. Total RNAs were extracted from HeLa-LTR-Luc cells in which PAAF1 or Spt6 had been knock down by a specific siRNA or HeLa-LTR-Luc cells that had been transfected with a control siRNA (“si Neg”). Differentially expressed genes in PAAF1 knock-down...
ORGANISM(S): Homo sapiens 
2012-05-28 | E-GEOD-32033 | biostudies-arrayexpress
ProteomicsmacroH2A is a BRCA1 ubiquitin ligase substrate
BRCA1/BARD1 is a macroH2A1-specific E3 ligase and implicates a role for macroH2A1 K123 ubiquitination in cellular senescence
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-11-04 | MSV000080319 | MassIVE
ProteomicsThe histone variant macroH2A1 is a BRCA1 ubiquitin ligase substrate
the histone variant macroH2A1 is BRCA1/BARD1 ubiquitinates macroH2A1at lysine 123 in vitro and in vivo.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-30 | MSV000081054 | MassIVE
GenomicsDynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis
Background: Despite the significant global loss of DNA hydroxymethylation marks in prostate cancer tissues, the locus-specific role of hydroxymethylation in prostate tumorigenesis is unknown. We characterized hydroxymethylation and methylation marks by performing whole-genome next generation sequenc...
ORGANISM(S): Homo sapiens 
2016-03-15 | E-GEOD-74464 | biostudies-arrayexpress
TranscriptomicsBRCT phosphoprotein recognition, but not E3 ligase activity, is essential for BRCA1 tumor suppression
It has been recognized that BRCA1, in the form of the BRCA1/BARD1 heterodimer, acting as an ubiquitin E3 ligase offered a possible mechanism to explain its pleiotrophic nature of BRCA1 activity. Our observation that mice lacking BRCA1 enzymatic activity are viable apart from male sterility was unex...
ORGANISM(S): Mus musculus 
2011-08-25 | E-GEOD-31673 | biostudies-arrayexpress
TranscriptomicsBisphenol A Regulates the Expression of DNA Repair Genes in Human Breast Epithelial Cells (expression data)
Xenoestrogens are part of a group of agents termed endocrine disruptors because of their capacity to perturb normal hormonal actions. It has been suggested that xenoestrogens may contribute to the development of hormone-dependent cancers, such as breast and endometrial cancers. Bisphenol A (BPA) is ...
ORGANISM(S): Homo sapiens 
2011-09-15 | E-GEOD-32158 | biostudies-arrayexpress
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