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TranscriptomicsGlucocorticoid-Dependent Hippocampal Transcriptome in Male Rats: Pathway-Specific Alterations with Aging
Although glucocorticoids (GCs) are known to exert numerous effects in the hippocampus, their chronic regulatory functions remain poorly understood. Moreover, evidence is inconsistent regarding the longstanding hypothesis that chronic GC exposure promotes brain aging/Alzheimer's disease. Here, we adr...
ORGANISM(S): Rattus norvegicus 
2013-07-22 | E-GEOD-37618 | biostudies-arrayexpress
TranscriptomicsMNNG treated Excherichia coli reveal new up or down regulated genes belonging to the Ada regulon
An oligonucleotide tiling array technology is utilized to measure the entire Escherichia coli transcriptome and its transcriptional changes after induction of the adaptive response by the alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Keywords: Gene expression during the adaptive res...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2010-05-06 | E-GEOD-13830 | biostudies-arrayexpress
TranscriptomicsUV treated Escherichia coli reveals a high number of differentially expressed regions and many novel transcripts
The transcriptional changes in Escherichia coli upon induction of the SOS response are investigated by utilizing custom designed oligonucleotide microarrays. Keywords: Gene expression during the SOS response in Escherichia coli Escherichia coli K-12 MG1655 single colony in five parallells was grown...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2010-05-06 | E-GEOD-13829 | biostudies-arrayexpress
UnknownA CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates.
Not available
S-EPMC2118677 | biostudies-literature
UnknownEffect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study.
Not available
S-EPMC3903533 | biostudies-literature
UnknownTotal Aβ42/Aβ40 ratio in plasma predicts amyloid-PET status, independent of clinical AD diagnosis.
Not available
S-EPMC7251518 | biostudies-literature
UnknownAlzheimer's disease and its progression reduce pyramidal cell gain and connectivity.
Not available
S-EPMC12553034 | biostudies-literature
TranscriptomicsSkeletal muscle PGC-1a mediates mitochondrial, but not metabolic, changes during calorie restriction.
Calorie restriction (CR) is a dietary intervention that extends lifespan and healthspan in a variety of organisms. CR improves mitochondrial energy production, fuel oxidation and reactive oxygen species scavenging in skeletal muscle and other tissues, and these processes are thought to be critical t...
ORGANISM(S): Mus musculus 
2012-02-04 | E-GEOD-34773 | biostudies-arrayexpress
UnknownAPOE and BDNF polymorphisms moderate amyloid β-related cognitive decline in preclinical Alzheimer's disease.
Not available
S-EPMC4759101 | biostudies-literature
UnknownEvaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer's Disease in the AIBL Study of Ageing.
Not available
S-EPMC7459751 | biostudies-literature
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