Sort   by:  
 Page size 
UnknownEpstein-Barr virus evades CD4+ T cell responses in lytic cycle through BZLF1-mediated downregulation of CD74 and the cooperation of vBcl-2.
Not available
S-EPMC3245307 | biostudies-literature
UnknownIndoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer.
Not available
S-EPMC6141803 | biostudies-literature
TranscriptomicsBurkitt Lymphoma Pathogenesis and Therapeutic Targets from Structural and Functional Genomics
Burkitt lymphoma (BL) can often be cured by intensive chemotherapy, but the toxicity of such therapy precludes its use in the elderly and in patients with endemic BL (eBL) in developing countries, necessitating new strategies. The normal germinal center B cell is the presumed cell of origin for both...
ORGANISM(S): Homo sapiens 
2012-08-16 | E-GEOD-35163 | biostudies-arrayexpress
TranscriptomicsNotch1-driven transcriptional changes in a mouse model of T-ALL
T-cell acute lymphoblastic leukemia (T-ALL) is an immature hematopoietic malignancy driven mainly by oncogenic activation of NOTCH1 signaling. In this study we used a mouse model of T-ALL through the overexpression of the intarcellular transcriptionally active part of Notch1 (N1-IC). This model fait...
ORGANISM(S): Mus musculus 
2012-01-10 | E-GEOD-34554 | biostudies-arrayexpress
UnknownGenetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.
Not available
S-EPMC3274628 | biostudies-literature
TranscriptomicsTranscription profiling of mouse Atm-/-,mTerc-/-,p53-/- triple knock-out lymphoma vs normal
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7607 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse Atm-/-,mTerc-/-,p53-/- triple knock out lymphoma vs. normal mouse DNA (GPL2884)
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7600 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization (CGH) of human melanoma vs. normal human samples
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7606 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human colon tumor vs normal DNA
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7604 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pancreatics tumors vs. normal tissue
Highly rearranged and mutated cancer genomes present major challenges in the identification of pathogenetic events driving the cancer process. Here, we engineered lymphoma-prone mice with chromosomal instability to assess the utility of mouse models in cancer gene discovery and the extent of cross-...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7599 | biostudies-arrayexpress
Sort   by:  
 Page size