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TranscriptomicsThe pattern of gene expression in human CD34(+) stem/progenitor cells
We have analyzed the pattern of gene expression in human primary CD34(+) stem/progenitor cells. We identified 42,399 unique serial analysis of gene expression (SAGE) tags among 106,021 SAGE tags collected from 2.5 x 10(6) CD34(+) cells purified from bone marrow. Of these unique SAGE tags, 21,546 mat...
ORGANISM(S): Homo sapiens 
2005-02-28 | E-GEOD-2346 | biostudies-arrayexpress
TranscriptomicsThe pattern of gene expression in human CD15+ myeloid progenitor cells
We performed a genome-wide analysis of gene expression in primary human CD151 myeloid progenitor cells. By using the serial analysis of gene expression (SAGE) technique, we obtained quantitative information for the expression of 37,519 unique SAGE-tag sequences. Of these unique tags, (i) 25% were de...
ORGANISM(S): Homo sapiens 
2008-10-03 | E-GEOD-13007 | biostudies-arrayexpress
TranscriptomicsDesign of a Diagnostic Pan-Pathogen Oligonucleotide Microarray including a sub-Array for Detection of Meningitis-Causing Bacterial Pathogens
Meningitis is a complex disease which can be caused by infection with either viral or bacterial pathogens. Viral meningitis is usually a sterile self-limiting disease with a good clinical prognosis, while bacterial meningitis is a potentially more serious disease with a higher mortality rate. Early ...
ORGANISM(S): Listeria monocytogenes 
2011-07-19 | E-GEOD-30794 | biostudies-arrayexpress
UnknownIdentification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study.
Not available
S-EPMC3595425 | biostudies-literature
UnknownT lymphoid differentiation in human bone marrow.
Not available
S-EPMC164518 | biostudies-literature
UnknownMLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16)(q23;p13.3).
Not available
S-EPMC23102 | biostudies-literature
TranscriptomicsGene Expression Profiles with Common Translocations in Acute Myeloid Leukemia (AML) using SAGE
SAGE was used to profile gene expression in leukemic myeloid progenitor cells of AML patients with t(8;21), t(15;17), t(9;11) and inv(16). Keywords: SAGE analysis of gene expression in leukemic myeloid progenitor cells isolated from bone marrow Bone marrow cells from 4 patients with de novo t(9;11),...
ORGANISM(S): Homo sapiens 
2005-11-30 | E-GEOD-3255 | biostudies-arrayexpress
TranscriptomicsIdentification of miR-181 target genes and a common prognostic gene signature in AML
Increased expression levels of miR-181 family members have been shown to be associated with favorable outcome in patients with cytogenetically normal acute myeloid leukemia. Here we show that increased expression of miR-181a and miR-181b is also significantly (P < .05; Cox regression) associated wit...
ORGANISM(S): Homo sapiens 
2012-04-03 | E-GEOD-30258 | biostudies-arrayexpress
UnknownmiR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia.
Not available
S-EPMC3710804 | biostudies-literature
TranscriptomicsPrognostic gene signature for AML
Acute myeloid leukemia (AML) is a heterogeneous disease in respect of molecular aberrations and prognosis. We used gene expression profiling of 562 patients treated in the German AMLCG 1999 trial to develop a gene signature that predicts survival in AML. Analysis of 562 samples (140 HGU-133plus2; 42...
ORGANISM(S): Homo sapiens 
2013-02-07 | E-GEOD-37642 | biostudies-arrayexpress
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