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ProteomicsMammalian oocytes store proteins in cytoplasmic lattices
Oocytes must accumulate and store maternal factors such as proteins during growth to sustain the first stages of embryonic development. How mammalian oocytes store maternal proteins is not understood. Here, we show that mouse and human oocytes store proteins on cytoplasmic lattices. With super-resol...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-23 | PXD038575 | Pride
Dia Cytoplasmic lattices Oocytes Lc-ms/ms 
ProteomicsIdentification of a Stable Stool Peptidomic Signature for Monitoring IBD Activity
Introduction Monitoring disease activity in inflammatory bowel disease (IBD) is essential for guiding therapy and preventing irreversible tissue damage. Colonoscopy, although the gold standard, is invasive and unsuitable for frequent monitoring, while fecal calprotectin lacks accuracy within its dia...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD074117 | Pride
Human Peptidomics Machine learning Inflammatory bowel disease Biomarker discovery Proteomics Stool Clinical mass spectrometry Nested cross validation Ibd activity 
ProteomicsPredictive Stool-Based Protein Biomarkers for the Classification of Crohn's Disease and Ulcerative Colitis Using a Machine Learning Approach
Background and Aim: Crohn's disease (CD) and ulcerative colitis (UC) are the two major chronic inflammatory bowel diseases (IBD). Although their symptoms are similar, their pathological features and clinical treatments differ. Currently, distinguishing between these diseases involves invasive proce...
ORGANISM(S): Homo sapiens (Human) 
2025-12-01 | PXD057120 | Pride
Crohn’s disease Inflammatory bowel disease (ibd) subtyping  protein biomarkers  dia mass spectrometry  quantitative proteomics  machine learning Ulcerative colitis. 
TranscriptomicsExpression data from wildtype and mec-3 mutant PVD/OLL sensory neurons in C. elegans
Nociceptive neurons develop a complex dendritic arbor to sense noxious stimuli, which enables animals to react to environmental insults and perform self-protective behaviours. The genetic programs controlling neuronal dendritic morphogenesis are poorly understood. In C. elegans, the PVD sensory neur...
ORGANISM(S): Caenorhabditis elegans 
2013-05-02 | E-GEOD-46530 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of mouse uterine epithelial cells isolated on morning of day 4 of pregnancy
Embryo implantation into a receptive endometrium is tightly regulated by a variety of maternal factors, including cytokines, growth factors and transcription factors. Previous studies identified the leukaemia inhibitory factor (LIF), produced in uterine glands, as an essential factor for implantatio...
ORGANISM(S): Mus musculus 
2013-07-01 | E-GEOD-44087 | biostudies-arrayexpress
ProteomicsClinical and immunological benefits of convalescent plasma therapy in severe COVID-19: insights from a single center open label randomised control trial
A randomised control trial was done to assess clinical and immunological benefits of passive immunization using convalescent plasma therapy (CPT), compared with standard of care, in severe COVID-19 patients presenting with acute respiratory distress syndrome (ARDS). Plasma abundance of a large panel...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025453 | Pride
Covid-19 Ards Convalescent plasma therapy (cpt) Acute respiratory distress syndrome (ards) Sawth-ms 
UnknownA prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts.
Not available
S-EPMC12056793 | biostudies-literature
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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