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ProteomicsLabel-free differential proteomics analysis of Ba/F3 expressing WT and mutant R98S RPL10
We recently identified a recurrent mutation in the ribosomal gene RPL10 that results in substitution of residue arginine 98 by a serine (R98S) of the ribosomal protein L10 (RPL10) in the contest of T-cell acute lymphoblastic leukemia (T-ALL). To gain insights into the mechanisms by which the RPL10 R...
ORGANISM(S): Mus musculus (Mouse) 
2017-11-28 | PXD005995 | Pride
Leukemia T-all Ribosomal mutation Rpl10 r98s 
UnknownThe T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling.
Not available
S-EPMC5669462 | biostudies-literature
UnknownThe ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Not available
S-EPMC6169730 | biostudies-literature
UnknownThe T-cell leukemia related rpl10-R98S mutant traps the 60S export adapter Nmd3 in the ribosomal P site in yeast.
Not available
S-EPMC5536393 | biostudies-literature
TranscriptomicsTranslatome analysis of the ribosomal protein L10 R98S mutation reveals altered serine metabolism in acute lymphoblastic leukemia [PolySeq]
Somatic ribosomal protein defects have recently been described in cancer, yet their impact on cellular transcription and translation remain poorly understood. Here we integrated mRNA sequencing, ribosome footprinting, polysomal RNA seq and quantitative mass spectrometry datasets obtained from an iso...
ORGANISM(S): Mus musculus 
2019-04-10 | GSE106528 | GEO
TranscriptomicsTranslatome analysis of the ribosomal protein L10 R98S mutation reveals altered serine metabolism in acute lymphoblastic leukemia [supplementaryRNA-seq]
Somatic ribosomal protein defects have recently been described in cancer, yet their impact on cellular transcription and translation remain poorly understood. Here we integrated mRNA sequencing, ribosome footprinting, polysomal RNA seq and quantitative mass spectrometry datasets obtained from an iso...
ORGANISM(S): Mus musculus 
2019-04-10 | GSE106530 | GEO
TranscriptomicsTranslatome analysis of the ribosomal protein L10 R98S mutation reveals altered serine metabolism in acute lymphoblastic leukemia [Ribo-seq]
Somatic ribosomal protein defects have recently been described in cancer, yet their impact on cellular transcription and translation remain poorly understood. Here we integrated mRNA sequencing, ribosome footprinting, polysomal RNA seq and quantitative mass spectrometry datasets obtained from an iso...
ORGANISM(S): Mus musculus 
2019-04-10 | GSE106529 | GEO
UnknownExploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells.
Not available
S-EPMC8811726 | biostudies-literature
GenomicsTranslatome analysis of the ribosomal protein L10 R98S mutation reveals altered serine metabolism in acute lymphoblastic leukemia [PolySeq]
Translatome analysis of the ribosomal protein L10 R98S mutation reveals altered serine metabolism in acute lymphoblastic leukemia [PolySeq]
PRJNA417117 | ENA
GenomicsTranslatome analysis of the ribosomal protein L10 R98S mutation reveals altered serine metabolism in acute lymphoblastic leukemia [supplementaryRNA-seq]
Translatome analysis of the ribosomal protein L10 R98S mutation reveals altered serine metabolism in acute lymphoblastic leukemia [supplementaryRNA-seq]
PRJNA417118 | ENA
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