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Multiple Myeloma (MM) is an hematological malignancy. MM cells are resistant to X-ray irradiations. We irradiated RPMI 8226 cancer cells with C-ions, which are more energetic than X-ray irradiations. We found that MM cells, RPMI 8226, are also resistant to C-ion irradiations. We used microarrays to ...
ORGANISM(S): Homo sapiens 
The oncogenic transcription factor TAL1/SCL is aberrantly overexpressed in over 40% of cases of T-cell acute lymphoblastic leukemia (T-ALL), emphasizing the importance of the TAL1-regulated transcriptional program in the molecular pathogenesis of T-ALL. Here we identify regions occupied by TAL1 and ...
ORGANISM(S): Homo sapiens 
Integrins are involved in the metastatic cascade and have been found to be responsible for intrinsic and acquired therapy resistance. Therefore, targeting integrins, or more specifically the signal transduction via integrin adhesion complexes (IACs), is a promising therapeutic opportunity to reduce ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD064756 | Pride
RNA-seq analysis in RPMI-8402 cells after knockout of MYC
RNA-seq analysis in RPMI-8402 cells after knockout of MYCN
Unravel the binding partners of RUNX1 transcription factor in RPMI-8402 NKX2-1 +/+ and NKX2-1 -/-.
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD057654 | Pride
ATAC-seq analysis for Jurkat nd RPMI-8402 T-ALL cells
RNA-seq analysis in RPMI-8402 cells after knockout of MYC and MYCN
Unravel the binding partners of NKX2-1 transcription factor in RPMI-8402 NKX2-1 +/+, using NKX2-1 -/- as negative control.
ORGANISM(S): Homo sapiens (Human) 
2025-12-15 | PXD057622 | Pride
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