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Effect of global or hypodermal depletion of RPOA-2
To investigate the contributions of hypodermal ribosome biogenesis to organism-wide growth, we established C.elegans strains where RPOA-2 can be depleted globally or particularly in hypodermis using auxin-inducible degradation (AID) system. We then performed gene expression profiling analysis using ...
ORGANISM(S): Caenorhabditis elegans 
2022-11-29 | GSE213367 | GEO
Functional experiments have found a significant increase in EPS synthesis upon the elimination of lactylation at RpoA Lys173. Thus we investigated the regulatory mechanisms by proteomic approah.
ORGANISM(S): Streptococcus mutans UA159 
2023-08-24 | PXD042680 | Pride
Effect of RNA Polymerase I (RPOA-2) degradation on transcription in intestinal cells dissected from adult C. elegans
Lactylation of RpoA-K173 affect the transcription Streptococcus mutans
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