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TranscriptomicsTranscripts regulated by elevated DKF-2 (WT background)
Transcriptional profiling was used to determine why DKF-2 (protein kinase D) deficiency and surfeit caused hypersensitivity and resistance, respectively, to a bacterial pathogen (P. aeruginosa 14). The studies show that DKF-2 contributes to C. elegans innate immunity by inducing expression of >75 ge...
ORGANISM(S): Caenorhabditis elegans 
2009-01-12 | E-GEOD-12456 | biostudies-arrayexpress
TranscriptomicsS2-Rubin + Ecdysone smallRNA RNA-Seq
modENCODE_submission_2973 This submission comes from a modENCODE project of Eric Lai. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We plan to generate a comprehensive catalog of expressed and functional microRNAs, and generate biological evidence for their re...
ORGANISM(S): Drosophila melanogaster 
2010-10-18 | E-GEOD-24542 | biostudies-arrayexpress
TranscriptomicsKc-Rubin + Ecdysone smallRNA RNA-Seq
modENCODE_submission_2974 This submission comes from a modENCODE project of Eric Lai. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We plan to generate a comprehensive catalog of expressed and functional microRNAs, and generate biological evidence for their re...
ORGANISM(S): Drosophila melanogaster 
2010-10-18 | E-GEOD-24543 | biostudies-arrayexpress
TranscriptomicsDermatofibrosarcoma protuberans
Dermatofibrosarcoma protuberans (DFSP) is an aggressive spindle cell neoplasm. It is associated with the chromosomal translocation, t(17:22), which fuses the COL1A1 and PDGFbeta genes. We determined the characteristic gene expression profile of DFSP and characterized DNA copy number changes in DFSP ...
ORGANISM(S): Homo sapiens 
2005-12-29 | E-GEOD-3930 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP array data for NF1-associated glioma risk
We performed whole genome SNP profiling on DNA samples from 236 patients with NF1, 123 with glimoa tumors and 113 without; 117 females and 119 males, together with 29 control samples. To identify polymorphisms in human adenylate cyclase 8 (AC8) which correlate with glioma risk in NF1 in a sex-speci...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-62215 | biostudies-arrayexpress
TranscriptomicsDynamic Pax3:Foxo1a expression of alveolar rhabdomyosarcoma
To define the specific function of Pax3:Foxo1a in G2/M stage, we compared whole mRNA expressions of mouse alveolar rhabdomyosarcoma tumor cells in G2/M stage (4N) with or without Pax3:Foko1a knockdown (si_YFP or si_control). The exerimental plan will include triplicate samples for sorted cells at G1...
ORGANISM(S): Mus musculus 
2014-03-19 | E-GEOD-41675 | biostudies-arrayexpress
TranscriptomicsF11R is a novel monocyte prognostic biomarker for malignant glioma [Seq]
Objective: Brain tumors (gliomas) contain large populations of infiltrating macrophages and recruited microglia, which in experimental murine glioma models promote tumor formation and progression. Among the barriers to understanding the contributions of these stromal elements to high-grade glioma (g...
ORGANISM(S): Mus musculus 
2013-11-13 | E-GEOD-46688 | biostudies-arrayexpress
TranscriptomicsBreed DNA-methylation in young offspring chicken with custom NimbleGen tiling array
To analyze DNA-methylation differences between two chicken breeds
ORGANISM(S): Gallus gallus 
2011-05-19 | E-MTAB-649 | biostudies-arrayexpress
TranscriptomicsBreed DNA-methylation in adult parent chicken with custom NimbleGen tiling array
To analyze DNA-methylation differences between two chicken breeds
ORGANISM(S): Gallus gallus 
2011-05-19 | E-MTAB-648 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of femoral bone tissue from red junglefowl and domestic White Leghorn chicken
The purpose of this experiment was to compare gene expression in femoral bone from red junglefowl and White Leghorn chicken (five of each sex and population). Total RNA was prepared from the femoral midshaft and 20 µg RNA was used in each cDNA synthesis reaction. In hybridization a common reference ...
ORGANISM(S): Gallus gallus 
2007-07-04 | E-TABM-241 | biostudies-arrayexpress
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