Rudolph Mark M - OmicsDI

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Histone H3K9me3 ChIP-seq of young adult C. elegans wildtype, and mutants emb-4 (qm31) and hrde-1 (tm1200)

This data set was generated to study the silencing of transposable elements by the histone H3K9me3 mark and its relevance for the nuclear RNAi pathway.

ORGANISM(S): Caenorhabditis elegans

2017-06-29 | E-MTAB-5662 | biostudies-arrayexpress

The activity of the Caenorhabditis elegans Aquarius helicase EMB-4 enables the nuclear RNAi machinery to engage nascent RNA

Germline small RNA pathways initiate silencing of repetitive elements in animals and an interplay of nuclear small RNAs and chromatin modifications maintain this silencing, protecting the germline from spreading of transposable elements. In C. elegans germline, nuclear argonaute protein HRDE-1 initi...

ORGANISM(S): Caenorhabditis elegans

2017-06-30 | PXD004416 | Pride

Gene expression in blastomeres after transfer of somatic cells into human oocytes

The exchange of the oocyte's genome with the genome of a somatic cell, followed by the derivation of pluripotent stem cells, could enable the generation of specific cell types affected in degenerative human diseases. Such cells, carrying the patient's genome, might be useful for cell replacement. H...

ORGANISM(S): Homo sapiens

2011-10-05 | E-GEOD-28022 | biostudies-arrayexpress

Fatigue in levodopa-naive subjects with Parkinson disease.

Not available

S-EPMC2937041 | biostudies-literature

Copy number variation in familial Parkinson disease.

Not available

S-EPMC3149037 | biostudies-literature

The genetic architecture of the human cerebral cortex.

Not available

S-EPMC7295264 | biostudies-literature

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.