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GenomicsCaenorhabditis elegans strain:N2, emb-4(hc60)
Analysis of differential gene expression under loss of emb-4
PRJDB14822 | ENA
ProteomicsThe activity of the Caenorhabditis elegans Aquarius helicase EMB-4 enables the nuclear RNAi machinery to engage nascent RNA
Germline small RNA pathways initiate silencing of repetitive elements in animals and an interplay of nuclear small RNAs and chromatin modifications maintain this silencing, protecting the germline from spreading of transposable elements. In C. elegans germline, nuclear argonaute protein HRDE-1 initi...
ORGANISM(S): Caenorhabditis elegans 
2017-06-30 | PXD004416 | Pride
Silac Nematode Emb-4 
TranscriptomicsThe Conserved Intron Binding Protein EMB-4 Plays Differential Roles in Germline Small RNA Pathways of C. elegans
Proper regulation of the germline transcriptome is essential for the maintenance of fertility and survival of a species. In C. elegans, germline transcriptome homeostasis hinges on a complex repertoire of small RNA pathways that act in both activating and silencing capacities. Our understanding of h...
ORGANISM(S): Caenorhabditis elegans 
2017-11-01 | GSE94455 | GEO
UnknownThe intron binding protein EMB-4 is an opposite regulator of cold and high temperature tolerance in Caenorhabditis elegans.
Not available
S-EPMC11309393 | biostudies-literature
GenomicsCaenorhabditis elegans
The Conserved Intron Binding Protein EMB-4 Plays Differential Roles in Germline Small RNA Pathways of C. elegans
PRJNA369752 | ENA
UnknownThe Helicase Aquarius/EMB-4 Is Required to Overcome Intronic Barriers to Allow Nuclear RNAi Pathways to Heritably Silence Transcription.
Not available
S-EPMC5554785 | biostudies-literature
GenomicsSmall RNA and total RNA sequencing of C. elegans with mutations in the hrde-1 and emb-4 genes
Small RNA and total RNA sequencing of C. elegans with mutations in the hrde-1 and emb-4 genes
PRJEB14792 | ENA
GenomicsHistone H3K9me3 ChIP-seq of young adult C. elegans wildtype, and mutants emb-4 (qm31) and hrde-1 (tm1200)
Histone H3K9me3 ChIP-seq of young adult C. elegans wildtype, and mutants emb-4 (qm31) and hrde-1 (tm1200)
PRJEB20485 | ENA
TranscriptomicsEffect of genetic knockdown Emb on enteric neuronal development in mice
EMB is a neural adhesion molecule that participates in the development of the enteric nervous system, but its specific mechanism in the development of enteric neurons remains unclear. We constructed Emb knockdown mice and performed SmartseqII transcriptome sequencing by flow sorting CD56+CD24+ intes...
ORGANISM(S): Mus musculus 
2026-05-20 | GSE327475 | GEO
TranscriptomicsGene expression profiling in Tie-2-Etv2 endothelial and/or hematopoietic precursors
Etv2 transgene was expressed from ROSA26 locus by removing floxed STOP cassette by Tie-2 Cre transgene. VE-Cad+/CD45= or VE-Cad+/CD45+ cells were sorted from control or tie-2-Etv2 E11.5 embryos (YS;yolk sac and Emb;embryo proper)and compared for gene expression in duplicate. Sample ID #1 VECAD+CD45-...
ORGANISM(S): Mus musculus 
2012-05-09 | E-GEOD-36516 | biostudies-arrayexpress
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