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UnknownTimely expression and activation of YAP1 in granulosa cells is essential for ovarian follicle development.
Not available
S-EPMC6704445 | biostudies-literature
UnknownMeiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.
Not available
S-EPMC10881575 | biostudies-literature
TranscriptomicsRedefining the Relevance of Established Cancer Cell Lines to the Study of Clinical Anti-Cancer Drug Resistance
Although in vitro models have been a cornerstone of anti-cancer drug development, their direct applicability to clinical cancer research has actually been uncertain. Using a state-of-the-art Taqman-based qRT-PCR assay, we investigated the multidrug resistance (MDR) transcriptome of six cancer types,...
ORGANISM(S): Homo sapiens 
2011-11-16 | E-GEOD-30034 | biostudies-arrayexpress
TranscriptomicsMultidrug Resistance-Linked Gene Signature Predicts Overall Survival of Patients with Primary Ovarian Serous Carcinoma
This study assesses the ability of multidrug resistance (MDR)-associated gene expression patterns to predict survival in patients with newly diagnosed carcinoma of the ovary. The scope of this research differs substantially from that of previous reports, as a very large set of genes was evaluated wh...
ORGANISM(S): Homo sapiens 
2012-04-19 | E-GEOD-30009 | biostudies-arrayexpress
TranscriptomicsZNF703 overexpression and/or knockdown in the breast cancer cell line MCF-7
The telomeric amplicon at 8p12 is common in ER+ breast cancers. Array-CGH and expression analyses of 1172 tumors revealed ZNF703/Zeppo1 was the single gene within the minimal amplicon and was amplified predominantly in the Luminal B subtype. Amplification was shown to correlate with increased gene a...
ORGANISM(S): Homo sapiens 
2011-03-26 | E-GEOD-23673 | biostudies-arrayexpress
UnknownABL1-mediated tyrosine phosphorylation of SYCP2 contributes to transcription-coupled homologous recombination and platinum resistance in ovarian cancer.
Not available
S-EPMC12409405 | biostudies-literature
UnknownMultidrug resistance-linked gene signature predicts overall survival of patients with primary ovarian serous carcinoma.
Not available
S-EPMC3376649 | biostudies-literature
UnknownRedefining the Relevance of Established Cancer Cell Lines to the Study of Clinical Anti-Cancer Drug Resistance
Not available
ORGANISM(S): Homo sapiens 
S-ECPF-GEOD-30034 | biostudies-other
UnknownTreatment of ovarian cancer by targeting the tumor stem cell-associated carbohydrate antigen, Sialyl-Thomsen-nouveau.
Not available
S-EPMC5955411 | biostudies-literature
UnknownPaclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-X<sub>L</sub> degradation to overcome cancer chemoresistance.
Not available
S-EPMC12262480 | biostudies-literature
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