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TranscriptomicsIntrinsic self-DNA triggers inflammatory disease dependent on STING (I)
Inflammatory diseases such as Aicardi-Goutieres Syndrome (AGS) and severe systemic lupus erythematosus (SLE) are generally lethal disorders that have been traced to defects in the exonuclease Trex1 (DNAseIII). Mice lacking Trex1 similarly die at an early age through comparable symptoms, including in...
ORGANISM(S): Mus musculus 
2014-07-09 | E-GEOD-59217 | biostudies-arrayexpress
TranscriptomicsIntrinsic self-DNA triggers inflammatory disease dependent on STING (II)
Inflammatory diseases such as Aicardi-Goutieres Syndrome (AGS) and severe systemic lupus erythematosus (SLE) are generally lethal disorders that have been traced to defects in the exonuclease Trex1 (DNAseIII). Mice lacking Trex1 similarly die at an early age through comparable symptoms, including in...
ORGANISM(S): Mus musculus 
2014-07-09 | E-GEOD-59218 | biostudies-arrayexpress
UnknownGut microbiota predict development of postdischarge diabetes mellitus in acute pancreatitis.
Not available
S-EPMC12911579 | biostudies-literature
UnknownGut microbiota predicts severity and reveals novel metabolic signatures in acute pancreatitis.
Not available
S-EPMC10894816 | biostudies-literature
MetabolomicsQuantitative 1H NMR metabolome profiling of Thai Jasmine rice (Oryza sativa) reveals primary metabolic response during brown planthopper infestation
Brown planthopper (BPH; Nilaparvata lugens) is a phloem feeding insect which is one of the most serious threats to rice crops in many countries throughout Asia. 1H NMR spectroscopy, combined with chemometrics, was used to analyze the polar metabolome from leaf extracts of Thai Jasmine rice (brown pl...
2016-11-25 | MTBLS151 | MetaboLights
TranscriptomicsInflammation-Driven Carcinogenesis is Mediated through STING [MEFs]
Chronic stimulation of innate immune pathways by microbial agents or damaged tissue is known to promote inflammation-driven tumorigenesis by unclarified mechanisms1-3. Here we demonstrate that mutagenic 7,12-dimethylbenz(a)anthracene (DMBA), etoposide or cisplatin induces nuclear DNA leakage into th...
ORGANISM(S): Mus musculus 
2014-05-31 | E-GEOD-57603 | biostudies-arrayexpress
TranscriptomicsInflammation-Driven Carcinogenesis is Mediated through STING [skin]
Chronic stimulation of innate immune pathways by microbial agents or damaged tissue is known to promote inflammation-driven tumorigenesis by unclarified mechanisms1-3. Here we demonstrate that mutagenic 7,12-dimethylbenz(a)anthracene (DMBA), etoposide or cisplatin induces nuclear DNA leakage into th...
ORGANISM(S): Mus musculus 
2014-05-31 | E-GEOD-57604 | biostudies-arrayexpress
UnknownCommon Practice of Percutaneous Drainage in Necrotising Pancreatitis-A Multicentre Retrospective Study (DRACULA).
Not available
S-EPMC12704573 | biostudies-literature
UnknownProteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease.
Not available
S-EPMC12705447 | biostudies-literature
UnknownComparative effectiveness of immediate antiretroviral therapy versus CD4-based initiation in HIV-positive individuals in high-income countries: observational cohort study.
Not available
S-EPMC4643831 | biostudies-literature
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