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TranscriptomicsTime series RNA-seq of Naïve CD4 positive T-cells undergoing differentiation towards T-helper 1.
In eukaryotes, mRNA abundance is often a poor proxy for protein abundance. Despite this, the majority of methods used to dissect function in mammalian biology involve measurements of mRNA, with the assumption that changes observed at the mRNA level are reflected at the protein level. The inability t...
ORGANISM(S): Homo sapiens 
2021-09-09 | E-MTAB-7775 | biostudies-arrayexpress
TranscriptomicsRNA-seq of SUPT1, LOUCY, JURKAT and DND41 after treatment with 5-azacytidine and Vitamin C
TET2 is a know tumorsuppressor gene involved in the demethylation of DNA. TET2 catalyses the conversion of 5-methyl cytosine (5-mC) to 5-hydroximethyl cytosine (5-hmC), an important step in the removal of methylation from the DNA. In T-All mutations in TET2 are rare, however we have found that it is...
ORGANISM(S): Homo sapiens 
2021-08-04 | E-MTAB-10512 | biostudies-arrayexpress
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