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MetabolomicsDysregulation of lipid metabolism and pathological inflammation in patients with COVID-19
In recent months, Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread throughout the world. COVID-19 patients show mild, moderate or severe symptoms with the latter ones requiring access to specialized intensive care. SARS-CoV-2 infec...
2023-02-01 | MTBLS6844 | MetaboLights
TranscriptomicsRNA-seq analysis of gene expression associated to altered gene dosage of DeIF6 during eye development in Drosophila melanogaster
We investigated the transcriptome of the eye imaginal discs and retinae in wild type (GMR/+) and DeIF6 overexpressing (GMR>DeIF6) flies at the third instar larva stage and pupa 40 hours after puparium formation.
ORGANISM(S): Drosophila melanogaster 
2019-07-18 | E-MTAB-5954 | biostudies-arrayexpress
TranscriptomicsComprehensive Transcriptome Profiling of Sporadic Medullary Thyroid Carcinoma
In this study, we performed the transcriptome analysis of a cohort comprising 72 (20 already published E-MTAB-11599) MTC (medullary thyroid carcinoma) specimens from patients with different genetic background (w/o RET or RAS mutations).
ORGANISM(S): Homo sapiens 
2026-01-07 | E-MTAB-15198 | biostudies-arrayexpress
ProteomicsAcetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
Histone modifying enzymes depend on the availability of cofactors, with acetyl-CoA being required for lysine acetyltransferase (KAT) activity. The discovery that mitochondrial acyl-CoA producing enzymes are also delivered to the nucleus, suggests that high concentrations of metabolites generated loc...
ORGANISM(S): Mus musculus (Mouse) 
2024-02-14 | PXD040937 | Pride
Histone post translational modifications 
ProteomicsTherapy-Induced Senescence Promotes Immunogenicity in Acute Myeloid Leukaemia Blasts through loss of PRC2-Mediated Gene Regulation
We employed mass spectrometry to perform an unbiased, quantitative analysis of histone modifications in newly diagnosed AML patients stratified by senescence competency
ORGANISM(S): Homo sapiens (Human) 
2026-08-07 | PXD065846 | Pride
Histone post-translationa modifications Acute myeloid leukaemia 
UnknownAccuracy of the clinical diagnosis of dementia with Lewy bodies (DLB) among the Italian Dementia Centers: a study by the Italian DLB study group (DLB-SINdem).
Not available
S-EPMC9213280 | biostudies-literature
UnknownBeyond RCTs: Short-term dual antiplatelet therapy in secondary prevention of ischemic stroke and transient ischemic attack.
Not available
S-EPMC11569538 | biostudies-literature
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