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ProteomicsMaintenance of neuronal TDP-43 expression requires axonal lysosome transport
TDP-43 mislocalization and pathology occurs across a range of neurodegenerative diseases, but the pathways that modulate TDP-43 in neurons are not well understood. We generated a Halo-TDP-43 knock-in iPSC line and performed a genome-wide CRISPR interference FACS-based screen to identify modifiers of...
ORGANISM(S): Homo sapiens (Human) 
2025-08-01 | PXD063206 | Pride
Ipsc neurons tdp43 
UnknownA customized Web portal for the genome of the ctenophore Mnemiopsis leidyi.
Not available
S-EPMC4234515 | biostudies-literature
UnknownThe homeodomain complement of the ctenophore Mnemiopsis leidyi suggests that Ctenophora and Porifera diverged prior to the ParaHoxozoa.
Not available
S-EPMC2959044 | biostudies-literature
UnknownFeasibility of Quality Measures for the Diagnosis and Treatment of Carpal Tunnel Syndrome.
Not available
S-EPMC8132589 | biostudies-literature
UnknownRisk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening.
Not available
S-EPMC4463475 | biostudies-literature
ProteomicsAltered mRNA transport and local translation in iNeurons with RNA binding protein knockdown
Neurons rely on mRNA transport and local translation to facilitate rapid protein synthesis in processes far from the cell body. These processes allow precise spatial and temporal control of translation and are mediated by RNA binding proteins (RBPs), including those known to be associated with neuro...
ORGANISM(S): Homo sapiens (Human) 
2025-07-30 | PXD054548 | Pride
Human Ipsc derived ineurons 
GenomicsComprehensive miRNA Sequence Analysis Reveals Survival Differences in Diffuse Large B-cell Lymphoma Patients
Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease, with 30-40% of patients failing to achieve complete responses to standard therapy. miRNAs are RNA molecules that attenuate expression of their mRNA targets. To characterize the DLBCL miRNome, we sequenced miRNAs from 92 DLBCL and 15 ben...
EGAS00001001025 | EGA
TranscriptomicsDevelopment and application of a microarray for assessing gene transcription in open ocean microbial communities.
A high-density oligonucleotide microarray that targets functional genes in marine microbial community was designed as a result of a multi-institutional effort. The design is based on nucleotide sequence data obtained with metagenomics and metatranscriptomics. The chip targets ~20000 gene sequences r...
ORGANISM(S): uncultured marine microorganism 
2013-03-07 | E-GEOD-44448 | biostudies-arrayexpress
GenomicsMarra_DLBCL_validation - samples
miRNA-seq Cohort of 140 Formalin Fixed Paraffin Embedded Diffuse Large B-cell Lymphoma Patient Samples
EGAD00001001073 | EGA
GenomicsMarra_DLBCL_discovery - samples
miRNA-seq Cohort of 92 Fresh Frozen Diffuse Large B-cell Lymphoma Patient Samples
EGAD00001001074 | EGA
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