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UnknownVandetanib in patients with locally advanced or metastatic medullary thyroid cancer: a randomized, double-blind phase III trial.
Not available
S-EPMC3675689 | biostudies-literature
MetabolomicsPhototrophic biofilm assembly in microbial-mat-derived unicyanobacterial consortia: model systems for the study of autotroph-heterotroph interactions
Microbial autotroph-heterotroph interactions influence biogeochemical cycles on a global scale, but the diversity and complexity of natural systems and their intractability to in situ manipulation make it challenging to elucidate the principles governing these interactions. The study of assembling p...
2014-06-24 | MTBLS75 | MetaboLights
GenomicGWAS of Preterm Birth

Preterm birth (PTB, born before 37 weeks of gestation) is a leading cause of neonatal mortality and post-natal morbidity. PTB affects one in nine all live births in the U.S. Notably, the highest rate of PTB occurs among African Americans (one in six). PTB is a complex trait, likely determined by ...

phs000332 | dbGaP
MetabolomicsGNPS - Effect of HDAC inhibition on metabolome of Aspergillus nidulans and discovery of many aspercryptins
Organic extracts of the wildtype mold species, Aspergillus nidulans, and a strain of A. nidulans where expression of the histone deacetylase (HDAC) RpdA was knocked-down. Biological triplicate of both strains are included.
ORGANISM(S): Aspergillus Nidulans Fgsc A4 (ncbitaxon:227321) 
2016-07-11 | MSV000079900 | GNPS
MetabolomicsGNPS DEIMoS: an open-source tool for processing high-dimensional mass spectrometry data
LC-IMS-MS/MS data from a large study of human plasma samples consisting of 40 quality control samples from the NIST Standard Reference Material 1950 and 112 study samples. An internal standard mixture consisting of D4-malonic acid, D4-succinic acid, D5-glycine, D4-citric acid, 13C6-fructose, D5-L-tr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-02-16 | MSV000088849 | GNPS
UnknownPrecision Population Medicine in Primary Care: The Sanford Chip Experience.
Not available
S-EPMC7994529 | biostudies-literature
GenomicsDistinct epigenomic landscapes of pluripotent and lineage-committed human cells
Human embryonic stem cells share identical genomic sequences with other lineage-committed cells yet possess the remarkable properties of self-renewal and pluripotency. It has been proposed that epigenetic regulatory mechanisms, involving DNA methylation and various chromatin modifications, are at l...
ORGANISM(S): Homo sapiens 
2009-10-13 | E-GEOD-17917 | biostudies-arrayexpress
GenomicsChromatin States in Human ES Cells Reveal Key Regulatory Sequences and Genes Involved in Pluripotency and Self-renewal
Human embryonic stem cells (hESCs) are offering a new therapeutic approach because of their unique ability to proliferate indefinitely in vitro and differentiate into multiple cell types. However, our understanding of the molecular mechanisms of pluripotency and self-renewal remain incomplete. To el...
ORGANISM(S): Homo sapiens 
2009-10-14 | E-GEOD-18292 | biostudies-arrayexpress
TranscriptomicsThe TMAO Generating Enzyme Flavin Monooxygenase 3 is a Central Regulator of Cholesterol Balance
Circulating levels of the gut microbe-derived metabolite trimethylamine-N-oxide(TMAO) have recently been linked to cardiovascular disease (CVD) risk. Here we performed transcriptional profiling in mouse models of altered reverse cholesterol transport (RCT), and serendipitously identified the TMAO-ge...
ORGANISM(S): Mus musculus 
2014-12-19 | E-GEOD-64326 | biostudies-arrayexpress
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.
Not available
S-EPMC12512976 | biostudies-literature
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