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ProteomicsQuantitative proteomics and in-cell cross-linking reveal cellular reorganisation during early neuronal differentiation of SH-SY5Y cells
The proteomes of undifferentiated and differentiated SH-SY5Y cells are characterised and compared. For this, neuronal differentiation using retinoic acid (RA) or a combination of RA and phorbol-12-myristat-13-acetate (RA/PMA) was explored. An MS-based label-free quantification approach is applied to...
ORGANISM(S): Homo sapiens (Human) 
2022-04-08 | PXD031054 | Pride
Proteomics Chemical cross-linking Mass spectrometry Protein networks Actin Sh-sy5y 
MetabolomicsUntargeted Plasma Lipidomics Identifies Oxidative Stress and Inflammation Signatures Associated with Recurrent Leg Ulcer Status in Sickle Cell Disease

Leg ulcers are among the most burdensome complications of sickle cell disease (SCD), yet the molecular determinants underlying ulcer susceptibility and recurrence remain incompletely characterized. We performed untargeted plasma lipidomics by LC–MS in 129 individuals with SCD from the REDS-III Br...

2025-12-19 | MTBLS13538 | MetaboLights
TranscriptomicsLack of microRNA-101 causes E-cadherin expression and function deregulation through EZH2 up-regulation in gastric cancer
Background & Aims: E-cadherin expression disruption is commonly observed in epithelial cancers and metastasis. Such event is also recognized as a crucial step in gastric cancer (GC) initiation and progression. As aberrant expression of microRNAs often perturb the normal expression and function of pi...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-33743 | biostudies-arrayexpress
UnknownKetamine, Etomidate, and Mortality in Emergency Department Intubations.
Not available
S-EPMC12706683 | biostudies-literature
UnknownEfficacy and safety of intramuscular administration of tixagevimab-cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial.
Not available
S-EPMC9173721 | biostudies-literature
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