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TranscriptomicsSingle-cell total RNA sequencing (VASA-seq) on index-sorted human colonic chip infected by wild-type S.Tm
We infected adult human intestine epithelium stem cell derived colonic chip with wild-type S.Tm 14028 with GFP label. To link intracellular replication levels to host response, we performed single-cell total RNA sequencing (VASA-seq) on index-sorted cells from GFPLow, GFPInt and GFPHigh levels.
ORGANISM(S): Homo sapiens 
2026-08-17 | E-MTAB-17486 | biostudies-arrayexpress
GenomicsscRNA-seq of FACS sorted epithelium after infections with S.Tm WT and mutants
scRNA-seq of FACS sorted epithelium after infections with S.Tm WT and mutants
PRJEB123775 | ENA
GenomicsInfection of LUVA mast cells with Salmonella Typhimurium wt and S.Tm ∆invG
Infection of LUVA mast cells with Salmonella Typhimurium wt and S.Tm ∆invG
PRJNA1206141 | ENA
GenomicsInfection of bone marrow-derived mast cells with Salmonella Typhimurium WT and S.Tm ∆invG
Infection of bone marrow-derived mast cells with Salmonella Typhimurium WT and S.Tm ∆invG
PRJNA926945 | ENA
TranscriptomicsscRNA-seq of FACS sorted epithelium after infections with S.Tm WT and mutants
To resolve host transcriptional responses induced by luminal or intracellular S.Tm 14028, we performed scRNA-seq on GFP+ (invaded, “In”) and GFP− (non-invaded, “Out”) cells infected with WTGFP, ΔSPI-1/2GFP, ΔssaVGFP (\"ΔSPI-2\"), or ΔsteEGFP S.Tm strains at 24 hpi
ORGANISM(S): Homo sapiens 
2026-08-17 | E-MTAB-17487 | biostudies-arrayexpress
TranscriptomicsInfection of LUVA mast cells with Salmonella Typhimurium wt and S.Tm ∆invG
Human LUVA mast cells were infected for 4 h with Salmonella Typhimurium SL1344 wildtype (wt) and S.Tm ∆invG to explore LUVA mRNA expression levels upon infection and the role of type-3-secretion-system mediated invasion.
ORGANISM(S): Homo sapiens 
2025-07-28 | GSE285817 | GEO
TranscriptomicsInfection of bone marrow-derived mast cells with Salmonella Typhimurium WT and S.Tm ∆invG
Murine bone marrow-derived mast cells (BMMC) were infected for 4 h with Salmonella Typhimurium SL1344 wildtype (WT) and S.Tm ∆invG to explore BMMC mRNA expression levels upon infection and the role of type-3-secretion-system mediated invasion.
ORGANISM(S): Mus musculus 
2023-12-08 | GSE223601 | GEO
GenomicsSingle-cell total RNA sequencing (VASA-seq) on index-sorted human colonic chip infected by wild-type S.Tm
Single-cell total RNA sequencing (VASA-seq) on index-sorted human colonic chip infected by wild-type S.Tm
PRJEB123774 | ENA
TranscriptomicsHost metabolic reprogramming during immune activation promotes intracellular bacterial survival (2DG)
Intracellular pathogens, such as Salmonella enterica serovar Typhimurium (S.Tm), are able to sense and respond to a changing host cell environment. Macrophages exposed to microbial products undergo metabolic changes that are increasingly understood to drive a productive inflammatory response. Howeve...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2022-10-19 | GSE139206 | GEO
TranscriptomicsHost metabolic reprogramming during immune activation promotes intracellular bacterial survival (glycerol or succinate)
Intracellular pathogens, such as Salmonella enterica serovar Typhimurium (S.Tm), are able to sense and respond to a changing host cell environment. Macrophages exposed to microbial products undergo metabolic changes that are increasingly understood to drive a productive inflammatory response. Howeve...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2022-10-19 | GSE139207 | GEO
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