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Immune checkpoint blockade (ICB) has revolutionized cancer treatment, but the therapeutic response is highly heterogeneous. A potential mode of resistance is tumor-intrinsic mechanisms leading to an immunosuppressive tumor microenvironment. However, the underlying interactive network remains elusive...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD059275 | Pride
Targeting tumor-intrinsic S100A1 augments antitumor immunity and potentiates immunotherapy efficacy
Immune checkpoint blockade (ICB) has revolutionized cancer treatment, but the therapeutic response is highly heterogeneous. A potential mode of resistance is tumor-intrinsic mechanisms leading to an immunosuppressive tumor microenvironment. However, the underlying interactive network remains elusive...
ORGANISM(S): Mus musculus 
2025-03-26 | GSE285657 | GEO
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