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TranscriptomicsRegulation of Transcription Termination by Glucosylated Hydroxymethyluracil, Base J, in L. major and T. brucei
Base J, β-D-glucosyl-hydroxymethyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. J is enriched at sites involved in RNA Polymerase (RNAP) II initiation and termination. We have previously demonstrated a role of J in regulating...
ORGANISM(S): Trypanosoma brucei 
2015-05-18 | E-GEOD-57621 | biostudies-arrayexpress
UnknownThe proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs).
Not available
S-EPMC11744864 | biostudies-literature
TranscriptomicsBase J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination
Base J and H3.V promote RNA Polymerase (RNAP) II termination within polycistronic gene clusters in the kinetoplastid species Trypanosoma brucei. Although base J has been shown to promote RNAP II termination in the related kinetoplastid species Leishmania major and Leishmania tarentolae, the role of ...
ORGANISM(S): Leishmania major 
2016-07-20 | E-GEOD-77632 | biostudies-arrayexpress
TranscriptomicsEpigenetic and transcriptional aberrations in human pluripotent stem cells reflect differences in reprogramming mechanisms [RNA-Seq]
Human pluripotent stem cells hold great potential for regenerative medicine, but available cell types have important limitations. While embryonic stem cells derived from fertilized embryos (IVF-ESCs) are considered the "gold standard" of pluripotency, they are allogeneic to potential recip...
ORGANISM(S): Homo sapiens 
2014-07-08 | E-GEOD-53094 | biostudies-arrayexpress
UnknownOne year of surgical mask testing at the University of Bologna labs: Lessons learned from data analysis.
Not available
S-EPMC9075986 | biostudies-literature
UnknownDevelopment of hybrid immunity during a period of high incidence of Omicron infections.
Not available
S-EPMC10749742 | biostudies-literature
UnknownChanges in socioeconomic resources and mental health after the second COVID-19 wave (2020-2021): a longitudinal study in Switzerland.
Not available
S-EPMC10035489 | biostudies-literature
UnknownSeroprevalence trends of anti-SARS-CoV-2 antibodies and associated risk factors: a population-based study.
Not available
S-EPMC9985433 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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