Sacco Michele M

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S-EPMC11580476 | biostudies-literature

Molecular sequelae of Nampt Inhibition in Human Multiple Myeloma cell line

Evaluation of specific coordinated pattern of transcriptional events consistent with anti-myeloma activity of FK866 (chemical Nampt inhibitor) 3 samples were analyzed using as control the untreated cells. Treated cells were cultured in presence of FK866 at concentration of 10nM for 6 and 24 hours.

ORGANISM(S): Homo sapiens

2012-11-05 | E-GEOD-35414 | biostudies-arrayexpress

Bulk RNA-seq of cerebral organoids investigating the role of CHD8 in cortical development

We used cerebral organoids generated from wildtype and CHD8 +/- human ES cells to study the effects of CHD8, one of the top ASD risk genes, on early cortical development. CHD8 +/- hESC were generated using the CRISPR/Cas9 system to create a deletion within the helicase domain. Cerebral organoids wer...

ORGANISM(S): Homo sapiens

2022-02-01 | E-MTAB-9933 | biostudies-arrayexpress

Enhanced recovery after bariatric surgery: a comprehensive survey-based analysis of ERABS actual clinical implementation in Italian bariatric centers.

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S-EPMC12540566 | biostudies-literature

TRIBE-2: a phase III, randomized, open-label, strategy trial in unresectable metastatic colorectal cancer patients by the GONO group.

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S-EPMC5466800 | biostudies-literature

Effectiveness and safety of dual antiplatelet therapy in patients with minor ischemic stroke or transient ischemic attack and cancer: A secondary analysis of the READAPT study.

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S-EPMC12018360 | biostudies-literature

Admission systolic blood pressure and short-term outcomes after dual antiplatelet therapy in patients with minor ischemic stroke or transient ischemic attack.