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RNA sequencing of mouse carotid arteries after sacubitril/valsartan treatment
We tested it in an animal model of myocardial infarction to ensure whether early initiation of dapagliflozin (DAPA), or different orders of combination with sacubitril-valsartan would result in a greater improvement of heart function than sacubitril-valsartan alone in post-myocardial infarction hear...
ORGANISM(S): Rattus norvegicus 
2023-04-13 | GSE229147 | GEO
Optimized alternative ordering of dapagliflozin and sacubitril-valsartan in post-myocardial infarction heart failure
Purpose: To get insight into mouse strain-dependent differences in vascular remodeling, we analyzed gene expression profiles of the ligated carotid arteries after interventions in C57BL/6J and 129X1/SvJ mice Methods: mRNA isolations from snap-frozen single carotids (n=3 per group) were conducted. Ti...
ORGANISM(S): Mus musculus 
2020-04-10 | GSE129689 | GEO
Background: It has been reported that sacubitril/valsartan can improve cardiac function in acute myocardial infarction (AMI) patients complicated by heart failure (HF). However, a number of patients cannot be treated successfully; this phenomenon is called sacubitril/valsartan resistance (SVR), and ...
ORGANISM(S): Homo sapiens 
2022-10-19 | GSE207882 | GEO
Faces in a rat model of MASH treated with Sacubitril/Valsartan
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