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TranscriptomicsGene expression of osteosarcoma cell (U2OS, MG63) lines relative to normal human osteoblasts (HOB)
Gain or loss of genes and deregulation of gene expression can result in cumulative and progressive disruptions of normal cellular functions. Cancer-specific changes in gene expression play an essential role in cancer occurrence, and ultimately lead to cancer-related self-sufficiency in growth signal...
ORGANISM(S): Homo sapiens 
2009-05-01 | E-GEOD-11414 | biostudies-arrayexpress
TranscriptomicsGene expression of human paediatric osteosarcoma tumour samples relative to normal human osteoblasts
Gain or loss of genes and deregulation of gene expression can result in cumulative and progressive disruptions of normal cellular functions. Cancer-specific changes in gene expression play an essential role in cancer occurrence, and ultimately lead to cancer-related self-sufficiency in growth signal...
ORGANISM(S): Homo sapiens 
2010-04-09 | E-GEOD-12865 | biostudies-arrayexpress
TranscriptomicsNLRP7 promotes trophoblast lineage differentiation, YY1 binding and alters CpG methylation
Genome wide DNA methylation profiling of hESC in the untransduced, scrambled control and with knockdown of NLRP7 in undifferentiated and BMP4 differentiated states using the Illumina HumanMethylation 450 BeadChip. Several genomic sites exhibit altered methylation upon knocking down NLRP7. Bisulphite...
ORGANISM(S): Homo sapiens 
2013-11-04 | E-GEOD-45727 | biostudies-arrayexpress
TranscriptomicsDiscovery of novel hypermethylated gene loci in prostate cancer using genome wide coverage CpG island microarrays
In order to identify methylation changes in prostate cancer, we performed a genome-wide analysis of DNA methylation using Agilent human CpG island arrays. We then chose specific genes to validate methylation both in the same cases as were hybridized to the array (using quantitative EpiTYPER analysis...
ORGANISM(S): Homo sapiens 
2009-03-26 | E-GEOD-15298 | biostudies-arrayexpress
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